Gene
nav3
- ID
- ZDB-GENE-021205-1
- Name
- neuron navigator 3
- Symbol
- nav3 Nomenclature History
- Previous Names
-
- cb419 (1)
- wu:fa05f06
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Enables actin binding activity. Acts upstream of or within liver morphogenesis and pancreas development. Located in Golgi apparatus; filopodium; and lamellipodium. Is expressed in several structures, including cardiovascular system; digestive system; liver primordium; nervous system; and periderm. Human ortholog(s) of this gene implicated in opiate dependence. Orthologous to human NAV3 (neuron navigator 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb419 (27 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Klein et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001715 | Calponin homology domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR003959 | ATPase, AAA-type, core |
| Family | IPR039041 | Nav/unc-53 family |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036872 | CH domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | ATPase, AAA-type, core | Calponin homology domain | CH domain superfamily | Nav/unc-53 family | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6YX31 | InterPro | 2411 | ||||||
| UniProtKB:Q5TZ18 | InterPro | 2269 | ||||||
| UniProtKB:A0A8M9Q0Q8 | InterPro | 2208 | ||||||
| UniProtKB:A0A8M9PHG5 | InterPro | 2412 | ||||||
| UniProtKB:A0A8M9PHH5 | InterPro | 2350 | ||||||
| UniProtKB:A0A8M9Q620 | InterPro | 1464 | ||||||
| UniProtKB:A0A8M9QBG6 | InterPro | 2383 | ||||||
| UniProtKB:A0A8M9QBH1 | InterPro | 1924 | ||||||
| UniProtKB:A0A8M9PUQ7 | InterPro | 2221 | ||||||
| UniProtKB:A0A8M9PUQ1 | InterPro | 2395 | ||||||
| UniProtKB:A0A8M3ARI4 | InterPro | 2373 | ||||||
| UniProtKB:A0A8M9QBF3 | InterPro | 2418 | ||||||
| UniProtKB:A0A8M9Q610 | InterPro | 2417 | ||||||
| UniProtKB:A0A8M9QBF8 | InterPro | 2409 | ||||||
| UniProtKB:A0A8M3B919 | InterPro | 2368 | ||||||
| UniProtKB:A0A8M9PUP3 | InterPro | 2411 | ||||||
| UniProtKB:A0A8M9Q0P5 | InterPro | 2410 | ||||||
| UniProtKB:A0A8M9Q614 | InterPro | 2403 | ||||||
| UniProtKB:A0A8M3ARS0 | InterPro | 2367 | ||||||
| UniProtKB:A0A8M9Q0Q3 | InterPro | 2389 | ||||||
| UniProtKB:A0A8M9PHG9 | InterPro | 2402 |
Interactions and Pathways
No data available
Plasmids
No data available