Gene

gapdhs

ID

ZDB-GENE-020913-1

Name

glyceraldehyde-3-phosphate dehydrogenase, spermatogenic

Symbol

gapdhs Nomenclature History

Previous Names

gapds (1)
cb350 (1)
fb71f08
fk58c09
wu:fb71f08
wu:fk58c09
zgc:76908

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including cardiovascular system; digestive system; nervous system; neural tube; and trigeminal placode. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

26 figures from 9 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb350 (26 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gapdhs Human Ortholog

No data available

Associated With gapdhs Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR020830	Glyceraldehyde 3-phosphate dehydrogenase, active site
Domain	IPR020828	Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
Domain	IPR020829	Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
Family	IPR006424	Glyceraldehyde-3-phosphate dehydrogenase, type I
Family	IPR020831	Glyceraldehyde/Erythrose phosphate dehydrogenase family
Homologous_superfamily	IPR036291	NAD(P)-binding domain superfamily