ZFIN ID: ZDB-GENE-020530-2
Gene Name: prostaglandin-endoperoxide synthase 2a
Gene Symbol: ptgs2a
Previous Names: Cox-2a (2), cox2 (1), ptgs2, zCOX-2 (1), fj02a10, unp1239, wu:fj02a10 (1)
Location: Chr: 2   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 10 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
  brain, carotid artery, eye, gill (all 22) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: sa10104, sa11800, sa16633, sa90
Knockdown reagents: MO1-ptgs2a (1), MO2-ptgs2a (1), MO3-ptgs2a (1), MO4-ptgs2a (1), MO5-ptgs2a (1)
PHENOTYPE
Data: Fig. S1 from North et al., 2007
Observed in: hematopoietic stem cell
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular response to organic cyclic compound (more)
Molecular Function peroxidase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000742 (1)
  • InterPro:IPR010255 (1)
  • InterPro:IPR019791 (1)
  • InterPro:IPR029576 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50292 (1)
  • Pfam:PF03098 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptgs2a-001 (1) 2135
    ncRNA ptgs2a-002 (1) 673
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ptgs2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ptgs2a Contained in: [BAC] CH73-147D18 (1) (order this)
    ptgs2a Contains: [SNP] rs3727618 (1), rs3727619 (1)
    ptgs2a Encodes: [EST] fj02a10 (1)
    [cDNA] MGC:66037 (1) (order this), MGC:77710 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_153657 (1) 2150 bp
    Genomic GenBank:CU570979 (1) 105710 bp
    Select Tool
    Polypeptide UniProtKB:Q6P4V3 (1) 601 aa
    Sequence Clusters UniGene:113864 (1)
    Sequence Information (all 18)
    OTHER ptgs2a GENE PAGES
  • Gene:246227 (1)
  • VEGA:OTTDARG00000034690 (1)
  • Ensembl(Zv9):ENSDARG00000004539 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ptgs2a 2  
    Human PTGS2 1 (1q25.2-q25.3)
  • OMIM:600262
  • Gene:5743
  • Mouse Ptgs2 1 ( 63.84 cM)
  • MGI:97798
  • Gene:19225
  • Orthology Details
    CITATIONS (55)