Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-020530-2
Gene Name: prostaglandin-endoperoxide synthase 2a
Gene Symbol: ptgs2a
Previous Names: Cox-2a (2), cox2 (1), ptgs2, zCOX-2 (1), fj02a10, unp1239, wu:fj02a10 (1)
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 10 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
  brain, carotid artery, eye, gill (all 22) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 1 genotype
Alleles: sa10104, sa11800, sa90
Knockdown reagents: MO1-ptgs2a (1), MO2-ptgs2a (1), MO3-ptgs2a (1), MO4-ptgs2a (1), MO5-ptgs2a (1)
PHENOTYPE
Data: Fig. S1 from North et al., 2007
Observed in: hematopoietic stem cell
GENE ONTOLOGY
Ontology GO Term
Biological Process response to chemical stimulus (more)
Molecular Function peroxidase activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000742 (1)
  • InterPro:IPR002007 (1)
  • InterPro:IPR010255 (1)
  • InterPro:IPR019791 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50292 (1)
  • Pfam:PF03098 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptgs2a-001 (1) 2135
    ncRNA ptgs2a-002 (1) 673
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM ptgs2a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ptgs2a Contained in: [BAC] CH73-147D18 (1) (order this)
    ptgs2a Contains: [SNP] rs3727618 (1), rs3727619 (1)
    ptgs2a Encodes: [EST] fj02a10 (1)
    [cDNA] MGC:66037 (1) (order this), MGC:77710 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_153657 (1) 2150 bp
    Genomic GenBank:CU570979 (1) 105710 bp
    Select Tool
    Polypeptide UniProtKB:Q8JH43 (1) 601 aa
    Sequence Clusters UniGene:113864 (1)
    Sequence Information (all 15)
    OTHER ptgs2a GENE PAGES
  • Gene:246227 (1)
  • VEGA:OTTDARG00000034690 (1)
  • Ensembl(Zv9):ENSDARG00000004539 (1)
  • MAPPING INFORMATION
    Chr: 2 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish ptgs2a 2  
    Human PTGS2 1 (1q25.2-q25.3)
  • OMIM:600262
  • Gene:5743
  • Mouse Ptgs2 1 ( 63.84)
  • MGI:97798
  • Gene:19225
  • CITATIONS (48)