ZFIN ID: ZDB-GENE-020419-37
Gene Name: UDP-glucuronate decarboxylase 1
Gene Symbol: uxs1
Previous Names: CHUNP6891, fj36b08, wu:fj36b08 (1), zgc:91980 (1)
Location: Chr: 9   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:91980]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  basal plate cartilage, brain, ceratobranchial cartilage, ceratohyal cartilage (all 15) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 14 Genotypes

Allele Type Mutagen Suppliers
hi954Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi3357Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18492 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • w60 Point Mutation ENU
    PHENOTYPE
    Data: 19 figures from 8 publications
    Observed in: cartilage element, cell junction organization, ceratobranchial 5 bone, ceratobranchial cartilage (all 47) expand
    DISEASE ASSOCIATED WITH uxs1 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chondroitin sulfate proteoglycan biosynthetic process (more)
    Cellular Component Golgi apparatus (more)
    Molecular Function UDP-glucuronate decarboxylase activity (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001509 (1)
  • InterPro:IPR016040 (1)
  • InterPro:IPR021761 (1)
  • Pfam:PF01370 (1)
  • Pfam:PF11803 (1)
  • EC:4.1.1.35 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA uxs1-001 (1) 2432
    uxs1-002 (1) 553
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM uxs1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    uxs1 Contained in: [BAC] CH73-385G5 (1) (order this)
    [Fosmid] CH1073-45B16 (1) (order this), CH1073-270F2 (1) (order this)
    uxs1 Encodes: [BAC END] zk16c14.sp6
    [EST] fj36b08 (1)
    [cDNA] MGC:91980 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173242 (1) 2472 bp
    Genomic GenBank:CU855778 (1) 81313 bp
    Select Tool
    Polypeptide UniProtKB:Q6GMI9 (1) 418 aa
    Sequence Clusters UniGene:79684 (1)
    Sequence Information (all 18)
    OTHER uxs1 GENE PAGES
  • Gene:192315 (1)
  • VEGA:OTTDARG00000033910 (1)
  • Ensembl(Zv9):ENSDARG00000056102 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT
    Zebrafish uxs1 9  
    Human UXS1 2 (2q12.2)
  • OMIM:609749
  • Gene:80146
  • Mouse Uxs1 1 ( 23.46 cM)
  • MGI:1915133
  • Gene:67883
  • Orthology Details
    CITATIONS (33)