Gene

ccna2

ID
ZDB-GENE-020418-1
Name
cyclin A2
Symbol
ccna2 Nomenclature History
Previous Names
  • cb671 (1)
  • chunp6924
  • wu:fi36f03
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Enables cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within retina development in camera-type eye. Predicted to be part of cyclin A2-CDK2 complex. Predicted to be active in cytoplasm; microtubule organizing center; and nucleus. Is expressed in several structures, including nervous system; neural tube; pectoral fin musculature; primordial germ cell; and tail bud. Orthologous to human CCNA2 (cyclin A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
hi2696TgTransgenic insertionExon 2UnknownDNA
Zebrafish International Resource Center (ZIRC) (order this)
hi3594aTgTransgenic insertionExon 2UnknownDNA
Zebrafish International Resource Center (ZIRC) (order this)
la011681TgTransgenic insertionUnknownUnknownDNA
Zebrafish International Resource Center (ZIRC) (order this)
sa14296Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
1 - 4 of 4
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-ccna2
    		Jin et al., 2021
    CRISPR2-ccna2
      		Jin et al., 2021
      CRISPR3-ccna2
        		Jin et al., 2021
        1 - 3 of 3
        Show
        Human Disease
        Associated With ccna2 Human Ortholog
        No data available
        Associated With ccna2 Via Experimental Models
        No data available
        Gene Ontology
        Protein Domains
        Domain, Family, and Site Summary
        Type InterPro ID Name
        Conserved_site IPR048258 Cyclins, cyclin-box
        Domain IPR004367 Cyclin, C-terminal domain
        Domain IPR006671 Cyclin, N-terminal
        Domain IPR013763 Cyclin-like domain
        Domain IPR032447 Cyclin-A, N-terminal APC/C binding region
        1 - 5 of 8 Show all
        Domain Details Per Protein
        Protein Length Cyclin Cyclin A/B-like Cyclin-A, N-terminal APC/C binding region Cyclin, C-terminal domain Cyclin-like domain Cyclin-like superfamily Cyclin, N-terminal Cyclins, cyclin-box
        UniProtKB:Q6NV43
        InterPro
        		428
        UniProtKB:Q98TA3
        InterPro
        		428
        1 - 2 of 2
        Transcripts
        Genome Browsers
        Type Name Annotation Method Has Havana Data Length (nt) Analysis
        mRNA ccna2-201 (1)
        Ensembl
        		Ensembl 5,312 nt
        ZFIN BLAST
        mRNA ccna2-202 (1)
        Ensembl
        		Ensembl 5,478 nt
        ZFIN BLAST
        mRNA ccna2-203 (1)
        Ensembl
        		Ensembl 5,400 nt
        ZFIN BLAST
        1 - 3 of 3
        Interactions and Pathways
        No data available
        Antibodies
        No data available
        Plasmids
        No data available
        Constructs
        No data available
        Marker Relationships
        Sequences
        Orthology
        Comparative Orthology
        Alliance
        Gene Tree
        Ensembl
        Citations
        Your Input Welcome
        We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.