ZFIN ID: ZDB-GENE-020208-1
Gene Name: T-cell leukemia, homeobox 2
Gene Symbol: tlx2
Previous Names: hox11l, Tlx-3a (1), tlx3a, ztlx-3a (1), zTlxA (1)
Location: Chr: 14 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 6 figures from 6 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Day 4 (96.0h-120.0h)
  inner ear anatomical region, Rohon-Beard neuron, statoacoustic (VIII) ganglion
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
la027578Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-tlx2 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tlx2 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process inner ear development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tlx2-001 (1) 1718
    tlx2-002 (1) 855
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tlx2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tlx2Contained in: [BAC] DKEY-285J18 (1) (order this)
    tlx2Encodes: [cDNA] MGC:158207 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_153651 (1) 1740bp
    Genomic GenBank:CR847836 (1) 62863bp
    Select Tool
    Polypeptide UniProtKB:A1A5U3 (1) 301aa
    Sequence Clusters UniGene:83676 (1)
    Sequence Information (all 17)
    OTHER tlx2 GENE PAGES
  • Gene:170781 (1)
  • VEGA:OTTDARG00000027854 (1)
  • Ensembl(GRCz10):ENSDARG00000011273 (1)
  • ORTHOLOGY for tlx2 (Chr: 14)
    Species Symbol Chromosome Accession # Evidence
    Human TLX2 2
  • Gene:3196
  • OMIM:604240
  • HGNC:5057
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (4)
    Mouse Tlx2 6
  • MGI:1350935
  • Gene:21909
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (2)
    Download Curated Orthology
    CITATIONS (32)