ZFIN ID: ZDB-GENE-020208-1
Gene Name: T-cell leukemia, homeobox 2
Gene Symbol: tlx2
Previous Names: hox11l, Tlx-3a (1), tlx3a, ztlx-3a (1), zTlxA (1)
Location: Chr: 14   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 6 figures from 6 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Larval:Day 4 (96.0h-120.0h)
  inner ear anatomical region, Rohon-Beard neuron, statoacoustic (VIII) ganglion
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-tlx2 (1)

Allele Type Mutagen Suppliers
la027578Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tlx2 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process inner ear development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tlx2-001 (1) 1718
    tlx2-002 (1) 855
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tlx2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tlx2 Contained in: [BAC] DKEY-285J18 (1) (order this)
    tlx2 Encodes: [cDNA] MGC:158207 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_153651 (1) 1740 bp
    Genomic GenBank:CR847836 (1) 62863 bp
    Select Tool
    Polypeptide UniProtKB:A1A5U3 (1) 301 aa
    Sequence Clusters UniGene:83676 (1)
    Sequence Information (all 16)
    OTHER tlx2 GENE PAGES
  • Gene:170781 (1)
  • VEGA:OTTDARG00000027854 (1)
  • Ensembl(Zv9):ENSDARG00000011273 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish tlx2 14  
    Human TLX2 2 (2p13.1)
  • OMIM:604240
  • Gene:3196
  • Mouse Tlx2 6 ( 35.94 cM)
  • MGI:1350935
  • Gene:21909
  • Orthology Details
    CITATIONS (32)