Gene
gria4a
- ID
- ZDB-GENE-020125-7
- Name
- glutamate receptor, ionotropic, AMPA 4a
- Symbol
- gria4a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Enables ionotropic glutamate receptor activity. Acts upstream of or within glial cell migration. Located in dendrite and neuronal cell body. Is expressed in nervous system. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human GRIA4 (glutamate ionotropic receptor AMPA type subunit 4).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 9 figures from Piller et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Neurodevelopmental disorder with or without seizures and gait abnormalities | 617864 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001320 | Ionotropic glutamate receptor, C-terminal |
Domain | IPR001828 | Receptor, ligand binding region |
Domain | IPR019594 | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain |
Family | IPR001508 | Ionotropic glutamate receptor, metazoa |
Family | IPR015683 | Ionotropic glutamate receptor |
Homologous_superfamily | IPR028082 | Periplasmic binding protein-like I |
Domain Details Per Protein
Protein | Length | Ionotropic glutamate receptor | Ionotropic glutamate receptor, C-terminal | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain | Ionotropic glutamate receptor, metazoa | Periplasmic binding protein-like I | Receptor, ligand binding region |
---|---|---|---|---|---|---|---|
UniProtKB:Q71E59
|
898 | ||||||
UniProtKB:A0A8M9QLC3
|
441 | ||||||
UniProtKB:A0A8M6Z9L8
|
898 | ||||||
UniProtKB:A0A8M6Z4D2
|
882 | ||||||
UniProtKB:A0A8M6Z2V5
|
882 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
gria4a-201
(1)
|
Ensembl | 3,021 nt | ||
mRNA |
gria4a-202
(1)
|
Ensembl | 1,407 nt |
Interactions and Pathways
No data available
Plasmids
No data available