Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-010625-1
Gene Name: dual specificity phosphatase 5
Gene Symbol: dusp5
Previous Names: wu:fc03b11, wu:fc86e02
Location: Chr: 22   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 14 figures from 6 publications
Directly Submitted Expression Data: 4 figures (7 images) from Thisse et al., 2004 [MGC:73256]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  angioblastic mesenchymal cell, artery, blood vasculature, common cardinal vein (all 18) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-dusp5 (1), MO2-dusp5 (1)
PHENOTYPE No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dephosphorylation (more)
Molecular Function MAP kinase tyrosine/serine/threonine phosphatase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000340 (1)
  • InterPro:IPR000387 (1)
  • InterPro:IPR001763 (1)
  • InterPro:IPR008343 (1)
  • InterPro:IPR016130 (1)
  • InterPro:IPR020422 (1)
  • InterPro:IPR024950 (1)
  • InterPro:IPR029021 (1)
  • PROSITE:PS00383 (1)
  • PROSITE:PS50054 (1)
  • PROSITE:PS50056 (1)
  • PROSITE:PS50206 (1)
  • Pfam:PF00581 (1)
  • Pfam:PF00782 (1)
  • EC:3.1.3.48 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dusp5-001 (1) 1522
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dusp5 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    dusp5 Contained in: [BAC] CH211-91I13 (1) (order this), CH211-194K1 (1) (order this), DKEY-262O11 (1)
    dusp5 Encodes: [EST] fc03b11, fc86e02
    [cDNA] MGC:73256 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212565 (1) 1541 bp
    Genomic GenBank:BX649552 163544 bp
    Select Tool
    Polypeptide UniProtKB:Q6PBT4 (1) 368 aa
    Sequence Clusters UniGene:77989 (1)
    Sequence Information (all 18)
    OTHER dusp5 GENE PAGES
  • Gene:114436 (1)
  • VEGA:OTTDARG00000010873 (1)
  • Ensembl(Zv9):ENSDARG00000019307 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish dusp5 22  
    Human DUSP5 10 (10q25)
  • OMIM:603069
  • Gene:1847
  • Mouse Dusp5 19 ( 47.98 cM)
  • MGI:2685183
  • Gene:240672
  • Orthology Details
    CITATIONS (25)