Gene

bco2l

ID
ZDB-GENE-010509-1
Name
beta-carotene 15, 15-dioxygenase 2, like
Symbol
bco2l Nomenclature History
Previous Names
  • bcdo2
  • bcdo2l
  • etID19516.5 (1)
  • fk59e08
  • wu:fk59e08 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Exhibits 9,10 (9', 10')-carotenoid-cleaving dioxygenase activity. Involved in negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway. Localizes to mitochondrion. Is expressed in blood cell; digestive system; head; pericardial region; and trunk.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Lobo et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bco2l Human Ortholog
No data available
Associated With bco2l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR004294 Carotenoid oxygenase
Domain Details Per Protein
Protein Length Carotenoid oxygenase
UniProtKB:A0A8M9PKL8 541
UniProtKB:Q90WH3 549
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA bco2l-201 (1) Ensembl 2,140 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bco2l polyclonal Mouse
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations