Gene
mapk14a
- ID
- ZDB-GENE-010202-2
- Name
- mitogen-activated protein kinase 14a
- Symbol
- mapk14a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Exhibits MAP kinase activity. Involved in several processes, including embryonic cleavage; p38MAPK cascade; and regulation of collateral sprouting in absence of injury. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including digestive system; immature eye; nervous system; otic vesicle; and pronephric duct. Orthologous to human MAPK14 (mitogen-activated protein kinase 14).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55209 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR017441 | Protein kinase, ATP binding site |
Conserved_site | IPR003527 | Mitogen-activated protein (MAP) kinase, conserved site |
Domain | IPR000719 | Protein kinase domain |
Family | IPR008352 | Mitogen-activated protein (MAP) kinase p38-like |
Family | IPR038784 | Mitogen-activated protein kinase 14 |
Family | IPR050117 | Mitogen-activated protein kinase |
Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
Protein | Length | Mitogen-activated protein kinase | Mitogen-activated protein kinase 14 | Mitogen-activated protein (MAP) kinase, conserved site | Mitogen-activated protein (MAP) kinase p38-like | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily |
---|---|---|---|---|---|---|---|---|
UniProtKB:B2GPM7
|
361 | |||||||
UniProtKB:A0A2R8QE41
|
361 | |||||||
UniProtKB:Q9DGE2
|
361 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
mapk14a-201
(1)
|
Havana | 2289 nt | |
mRNA |
mapk14a-203
(1)
|
Ensembl | 1913 nt | |
ncRNA |
mapk14a-002
(1)
|
Havana | 736 nt |
Interactions and Pathways
Plasmids