Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-010131-7
Gene Name: trypsin
Gene Symbol: try
Previous Names: wu:fb57g08 (1), zgc:109701
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 96 figures from 48 publications
Directly Submitted Expression Data: 7 figures (2 images) from Thisse et al., 2004 [MGC:109701]
  11 figures (18 images) from Rauch et al., 2003 [fb60g08]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
  exocrine cell, exocrine pancreas, gut, heart (all 10) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa16247
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Pancreatitis, hereditary 167800
Trypsinogen deficiency 614044
GENE ONTOLOGY
Ontology GO Term
Biological Process proteolysis (more)
Molecular Function catalytic activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001254 (1)
  • InterPro:IPR001314 (1)
  • InterPro:IPR009003 (1)
  • InterPro:IPR018114 (1)
  • PROSITE:PS00134 (1)
  • PROSITE:PS00135 (1)
  • PROSITE:PS50240 (1)
  • Pfam:PF00089 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA try-001 (1) 871
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM try No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    try Contained in: [BAC] DKEYP-84F3 (1)
    try Encodes: [EST] fb57g08, fb60g08 (1)
    [cDNA] MGC:109701 (1) (order this), MGC:193019 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131708 (1) 845 bp
    Genomic GenBank:BX539313 (1) 215158 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q561Z7 (1) 247 aa
    Sequence Clusters UniGene:75547 (1)
    Sequence Information (all 25)
    OTHER try GENE PAGES
  • Gene:65223 (1)
  • VEGA:OTTDARG00000021061 (1)
  • Ensembl(Zv9):ENSDARG00000042993 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish try 16  
    Human PRSS1 7 (7q34)
  • OMIM:276000
  • Gene:5644
  • Orthology Details
    CITATIONS (85)