Gene
s1pr1
- ID
- ZDB-GENE-001228-2
- Name
- sphingosine-1-phosphate receptor 1
- Symbol
- s1pr1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Enables lysophosphatidic acid receptor activity. Involved in G protein-coupled receptor signaling pathway. Acts upstream of or within several processes, including circulatory system development; mesodermal cell migration; and negative regulation of angiogenesis. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including cardiovascular system; fin bud; nervous system; neural tube; and pleuroperitoneal region. Orthologous to human S1PR1 (sphingosine-1-phosphate receptor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 1 |
|---|---|---|---|---|---|
|
UniProtKB:Q1LV63
|
362 | ||||
|
UniProtKB:Q9DDK4
|
362 |
Interactions and Pathways
No data available
Plasmids
No data available