Gene
mbl2
- ID
- ZDB-GENE-000427-2
- Name
- mannose binding lectin 2
- Symbol
- mbl2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to be part of collagen trimer. Predicted to be active in extracellular space and multivesicular body. Is expressed in liver. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bacterial infectious disease (multiple); fungal infectious disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to several human genes including MBL2 (mannose binding lectin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Wang et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Chronic infections, due to MBL deficiency} | 614372 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR018378 | C-type lectin, conserved site |
| Domain | IPR001304 | C-type lectin-like |
| Domain | IPR033990 | Collectin, C-type lectin-like domain |
| Family | IPR050801 | Calcium-Dependent Lectins in Immunity and Development |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Repeat | IPR008160 | Collagen triple helix repeat |
Domain Details Per Protein
| Protein | Length | Calcium-Dependent Lectins in Immunity and Development | Collagen triple helix repeat | Collectin, C-type lectin-like domain | C-type lectin, conserved site | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q504I3
|
251 |
Interactions and Pathways
No data available
Plasmids
No data available