| ZFIN ID: ZDB-GENE-000403-1 |
| Gene Name: | axin 1 |
|---|---|
| Gene Symbol: | axin1 |
| Previous Names: | masterblind, mbl, wu:fi22e03, wu:fj14c08, wu:fk11b03 (1), zgc:109872 |
| Nomenclature History | |
| All Expression Data: | 3 figures from 3 publications |
| Wild-type Stages, Structures: | Cleavage:16-cell (1.5h-1.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) |
|---|---|
| forebrain, habenula, midbrain, unspecified | |
| Curated Microarray Expression: | GEO (1) |
| Mutant lines: | 10 genotypes |
| Alleles: | la028927Tg, tm13, tm213 |
| Knockdown reagents: | MO1-axin1 (1), MO2-axin1 (1) |
| Data: | 21 figures from 9 publications |
| Observed in: |
adenohypophysis,
anterior commissure,
blood circulation,
brain
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| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Caudal duplication anomaly | 607864 |
| Hepatocellular carcinoma, somatic | 114550 |
| Ontology | GO Term |
|---|---|
| Biological Process | activation of JUN kinase activity (more) |
| Cellular Component | beta-catenin destruction complex (more) |
| Molecular Function | protein homodimerization activity (more) |
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| Tg(hsp70l:GFP-axin1) |
| axin1 Contains: | [SNP] rs3727728 (1), rs3727729 (1) |
| axin1 Encodes: |
[EST]
fi22e03 (1),
fj14c08 (1),
fk11b03 (1)
[cDNA] MGC:109872 (1) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_131503 (1) | 4742 bp |
Select Tool
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| Genomic | GenBank:CU138533 (1) | 115648 bp | |
| Polypeptide | UniProtKB:P57094 (1) | 835 aa |
Select Tool
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| Sequence Clusters | UniGene:80549 (1) |
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| Chr: 3 Details | View Map: Merged Individual Panels |
| Evidence | ||||||
|---|---|---|---|---|---|---|
| Species | Symbol | Chromosome (Position) | Accession # | AA | ||
| Zebrafish | axin1 | 3 |
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| Human | AXIN1 | 16 (16p13.3) |
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| Mouse | Axin1 | 17 ( 13.07) |
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