ZFIN ID: ZDB-GENE-060803-2
Gene Name: integrin, beta 1a
Gene Symbol: itgb1a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function CONTRIBUTES TO C-X3-C chemokine binding IBA PANTHER:PTN002560762, UniProtKB:P05556 Gaudet et al., 2010
collagen binding involved in cell-matrix adhesion IBA PANTHER:PTN002560762, UniProtKB:P05556 Gaudet et al., 2010
fibronectin binding IBA PANTHER:PTN002560762, RGD:2927, UniProtKB:P05556 Gaudet et al., 2010
fibronectin binding IGI itga5, fn1a J├╝lich et al., 2009
integrin binding IBA PANTHER:PTN000801545, MGI:MGI:96612, MGI:MGI:96615, RGD:2927, MGI:MGI:96614, UniProtKB:P05106, MGI:MGI:96610 Gaudet et al., 2010
CONTRIBUTES TO laminin binding IBA PANTHER:PTN002560762, MGI:MGI:96610 Gaudet et al., 2010
protein heterodimerization activity IPI UniProtKB:B3DJJ0 2 Publications
signaling receptor activity IEA InterPro:IPR027071 ZFIN Electronic Annotation
Cellular Component cell junction IEA UniProtKB-KW:KW-0965 ZFIN Electronic Annotation
cell projection IEA UniProtKB-KW:KW-0966 ZFIN Electronic Annotation
focal adhesion IBA PANTHER:PTN000801545, UniProtKB:P18564, RGD:2927, MGI:MGI:96614, UniProtKB:P07228, FB:FBgn0004657, UniProtKB:P05106 Gaudet et al., 2010
focal adhesion IBA PANTHER:PTN000801545, UniProtKB:P18564, RGD:2927, MGI:MGI:96614, UniProtKB:P07228, FB:FBgn0004657, UniProtKB:P05556, UniProtKB:P05106 Gaudet et al., 2010
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
integrin complex IEA InterPro:IPR027071 ZFIN Electronic Annotation
invadopodium membrane IEA UniProtKB-SubCell:SL-0290 UniProt-GOA
lamellipodium IEA UniProtKB-SubCell:SL-0291 UniProt-GOA
melanosome IEA UniProtKB-SubCell:SL-0161 UniProt-GOA
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
plasma membrane IEA UniProtKB-KW:KW-1003 ZFIN Electronic Annotation
ruffle membrane IEA UniProtKB-SubCell:SL-0301 UniProt-GOA
Biological Process cell adhesion IEA InterPro:IPR027071 ZFIN Electronic Annotation
cell adhesion IEA UniProtKB-KW:KW-0130 ZFIN Electronic Annotation
cell adhesion mediated by integrin IBA PANTHER:PTN000801545, UniProtKB:P18564, MGI:MGI:96615, RGD:2927, FB:FBgn0004657, UniProtKB:P05556, UniProtKB:P05106 Gaudet et al., 2010
cell migration IBA PANTHER:PTN000801545, UniProtKB:A0A0R4IR57, MGI:MGI:96616, FB:FBgn0004657, MGI:MGI:96610 Gaudet et al., 2010
cell migration IBA UniProtKB:A0A0R4IR57, PANTHER:PTN000801545, MGI:MGI:96616, FB:FBgn0004657, MGI:MGI:96610 Gaudet et al., 2010
cell-matrix adhesion IBA UniProtKB:P18084, PANTHER:PTN000801545, UniProtKB:P16144, MGI:MGI:96612, UniProtKB:P26010, UniProtKB:P05556, UniProtKB:P05106, MGI:MGI:96610, UniProtKB:P05107 Gaudet et al., 2010
cell-matrix adhesion IBA UniProtKB:P18084, UniProtKB:P26012, PANTHER:PTN000801545, UniProtKB:P16144, MGI:MGI:96612, UniProtKB:P26010, UniProtKB:P05556, UniProtKB:P05106, UniProtKB:P05107, MGI:MGI:96610 Gaudet et al., 2010
cell-matrix adhesion IEA InterPro:IPR027071 ZFIN Electronic Annotation
glial cell development IMP CRISPR1-itgb1a, CRISPR2-itgb1a Charlton-Perkins et al., 2019
integrin-mediated signaling pathway IBA UniProtKB:P18084, PANTHER:PTN000801545, UniProtKB:P26010, MGI:MGI:96614, UniProtKB:P05556, FB:FBgn0004657, MGI:MGI:96611, UniProtKB:P53714, UniProtKB:P05107 Gaudet et al., 2010
integrin-mediated signaling pathway IEA InterPro:IPR027071 ZFIN Electronic Annotation
integrin-mediated signaling pathway IEA UniProtKB-KW:KW-0401 ZFIN Electronic Annotation
positive regulation of sprouting angiogenesis IGI egfl6 Wang et al., 2016
positive regulation of sprouting angiogenesis IMP MO1-itgb1a Wang et al., 2016
retina development in camera-type eye IMP CRISPR1-itgb1a, CRISPR2-itgb1a Charlton-Perkins et al., 2019