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General Information
ZIRC
ZFIN ID: ZDB-GENE-030903-5
Gene Name: FYN proto-oncogene, Src family tyrosine kinase a
Gene Symbol: fyna
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function ATP binding IEA InterPro:IPR000719 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR017441 ZFIN Electronic Annotation
ATP binding IEA UniProtKB-KW:KW-0067 ZFIN Electronic Annotation
kinase activity IEA UniProtKB-KW:KW-0418 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
non-membrane spanning protein tyrosine kinase activity IBA WB:WBGene00005077, MGI:MGI:95527, UniProtKB:P51451, UniProtKB:Q13882, PANTHER:PTN002521528, UniProtKB:P09769 Gaudet et al., 2010
non-membrane spanning protein tyrosine kinase activity IEA EC:2.7.10.2 ZFIN Electronic Annotation
nucleotide binding IEA UniProtKB-KW:KW-0547 ZFIN Electronic Annotation
protein kinase activity IDA Sharma et al., 2005
protein kinase activity IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR001245 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR008266 ZFIN Electronic Annotation
protein tyrosine kinase activity IEA InterPro:IPR020635 ZFIN Electronic Annotation
protein tyrosine kinase activity IEA UniProtKB-KW:KW-0829 ZFIN Electronic Annotation
signaling receptor binding IBA RGD:2641, FB:FBgn0262733, RGD:621017, RGD:620795, PANTHER:PTN002521528, UniProtKB:P12931 Gaudet et al., 2010
transferase activity IEA UniProtKB-KW:KW-0808 ZFIN Electronic Annotation
Cellular Component cytoplasm IEA UniProtKB-KW:KW-0963 ZFIN Electronic Annotation
cytosol IDA Rongish et al., 2000
extrinsic component of cytoplasmic side of plasma membrane IBA UniProtKB:P08631, PANTHER:PTN002521528 Gaudet et al., 2010
nucleus IDA Rongish et al., 2000
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
Biological Process adherens junction maintenance IGI yes1 Sempou et al., 2016
cell differentiation IBA RGD:621423, PANTHER:PTN002521528 Gaudet et al., 2010
convergent extension involved in gastrulation IGI MO1-fyna,fynb, MO1-wnt11f2, MO1-yes1 Jopling et al., 2005
convergent extension involved in gastrulation IGI MO1-fyna,fynb, MO1-wnt5b, MO1-yes1 Jopling et al., 2005
convergent extension involved in gastrulation IGI MO1-fyna,fynb, MO1-yes1 Jopling et al., 2005
gastrulation with mouth forming second IMP Sharma et al., 2005
multicellular organism development IEA UniProtKB-KW:KW-0217 ZFIN Electronic Annotation
myelination IMP MO1-fyna,fynb Czopka et al., 2013
myelination IMP ue5Tg Czopka et al., 2013
peptidyl-tyrosine autophosphorylation IBA WB:WBGene00005077, UniProtKB:Q9H3Y6, PANTHER:PTN002521528 Gaudet et al., 2010
phosphorylation IEA UniProtKB-KW:KW-0418 ZFIN Electronic Annotation
protein autophosphorylation IDA Sharma et al., 2005
protein phosphorylation IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR001245 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR008266 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR020635 ZFIN Electronic Annotation
regulation of cell population proliferation IBA UniProtKB:P07332, PANTHER:PTN002521528 Gaudet et al., 2010
regulation of cytosolic calcium ion concentration IMP Sharma et al., 2005
regulation of protein kinase activity IGI MO1-fyna,fynb, MO1-yes1 2 Publications
transmembrane receptor protein tyrosine kinase signaling pathway IBA UniProtKB:P07948, PANTHER:PTN002521528 Gaudet et al., 2010