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General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-4490
Gene Name: endothelial PAS domain protein 1a
Gene Symbol: epas1a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA-binding transcription factor activity IEA InterPro:IPR001067 ZFIN Electronic Annotation
DNA-binding transcription factor activity, RNA polymerase II-specific IBA UniProtKB:Q8IUM7, MGI:MGI:2664186, PANTHER:PTN000548738, MGI:MGI:106918 Gaudet et al., 2010
protein dimerization activity IEA InterPro:IPR011598 ZFIN Electronic Annotation
protein dimerization activity IEA InterPro:IPR036638 ZFIN Electronic Annotation
Cellular Component cytoplasm IEA InterPro:IPR001067 ZFIN Electronic Annotation
nucleus IBA MGI:MGI:109205, MGI:MGI:109169, MGI:MGI:1859778, FB:FBgn0262139, FB:FBgn0039411, MGI:MGI:1351610, MGI:MGI:98306, MGI:MGI:2664186, MGI:MGI:98307, FB:FBgn0266411, MGI:MGI:106918, FB:FBgn0004666, RGD:70332, RGD:61928, RGD:68404, WB:WBGene00001851, PANTHER:PTN000548738, UniProtKB:Q16665 Gaudet et al., 2010
nucleus IBA MGI:MGI:109205, MGI:MGI:109169, MGI:MGI:1859778, FB:FBgn0262139, FB:FBgn0039411, MGI:MGI:1351610, MGI:MGI:98306, MGI:MGI:98307, MGI:MGI:2664186, FB:FBgn0266411, MGI:MGI:106918, FB:FBgn0004666, RGD:70332, RGD:61928, RGD:68404, WB:WBGene00001851, PANTHER:PTN000548738, UniProtKB:Q16665 Gaudet et al., 2010
nucleus IEA InterPro:IPR001067 ZFIN Electronic Annotation
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
transcription factor complex IEA InterPro:IPR001067 ZFIN Electronic Annotation
Biological Process hematopoietic stem cell differentiation IGI epas1a Gerri et al., 2018
hematopoietic stem cell differentiation IGI hif1ab Gerri et al., 2018
hematopoietic stem cell differentiation IGI epas1b Gerri et al., 2018
hematopoietic stem cell differentiation IGI hif1aa Gerri et al., 2018
hematopoietic stem cell differentiation IMP kca3Tg; kca4Tg Gerri et al., 2018
hematopoietic stem cell differentiation IMP kca3Tg; ubs4Tg Gerri et al., 2018
hematopoietic stem cell differentiation IMP hif1aabns89/bns89; hif1abbns90/bns90 Gerri et al., 2018
hematopoietic stem cell differentiation IMP notch1abns135/bns135 Gerri et al., 2018
hematopoietic stem cell differentiation IMP notch1bsa11236/sa11236 Gerri et al., 2018
hematopoietic stem cell differentiation IMP epas1abns231/bns231 ; epas1bbns232/bns232 Gerri et al., 2018
Notch signaling pathway IGI epas1b Gerri et al., 2018
Notch signaling pathway IMP epas1abns231/bns231 ; epas1bbns232/bns232 Gerri et al., 2018
positive regulation of transcription by RNA polymerase II IBA MGI:MGI:109169, FB:FBgn0262139, FB:FBgn0039411, UniProtKB:Q8IUM7, MGI:MGI:2664186, FB:FBgn0266411, MGI:MGI:106918, UniProtKB:Q99814, PANTHER:PTN001127032, RGD:70332, WB:WBGene00000521, RGD:61928, RGD:68404, WB:WBGene00001851, UniProtKB:Q16665 Gaudet et al., 2010
regulation of transcription by RNA polymerase II IBA UniProtKB:Q9Y2N7, FB:FBgn0039411, PANTHER:PTN000548738 Gaudet et al., 2010
regulation of transcription, DNA-templated IEA InterPro:IPR001067 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR013767 ZFIN Electronic Annotation