Phenotype Summary

Phenotypes

Publication	Data		Phenotype
Yu et al., 2021	Fig. 3		brain dopaminergic neuron decreased amount, abnormal dopaminergic neuron ab1-th labeling decreased amount, abnormal
Zhu et al., 2020	Fig. 1		brain blood coagulation increased occurrence, abnormal brain blood coagulation occurrence, ameliorated heart contraction decreased rate, abnormal pericardium edematous, abnormal
	Fig. 2		blood circulation disrupted, abnormal brain vasculature closed, abnormal locomotory behavior decreased occurrence, abnormal
	Fig. 3		brain blood coagulation occurrence, ameliorated
	Fig. 4		whole organism nitric oxide decreased amount, abnormal
	Fig. 5		brain apoptotic process increased occurrence, abnormal whole organism baxa expression increased amount, abnormal whole organism bdnf expression decreased amount, abnormal whole organism casp3a expression increased amount, abnormal whole organism casp7 expression increased amount, abnormal whole organism casp9 expression increased amount, abnormal whole organism gdnfa expression decreased amount, abnormal whole organism mbpa expression decreased amount, abnormal whole organism tuba1b expression decreased amount, abnormal
	Fig. 6		brain inflammatory response increased occurrence, abnormal brain neutrophil chemotaxis increased occurrence, abnormal whole organism il10 expression increased amount, abnormal whole organism il1b expression increased amount, abnormal whole organism il6 expression increased amount, abnormal whole organism nfkb1 expression increased amount, abnormal whole organism tnfa expression increased amount, abnormal whole organism reactive oxygen species increased amount, abnormal
Suppiger et al., 2016	Fig. 7		whole organism decreased life span, abnormal
Rajaram et al., 2014	Fig. 2		green sensitive photoreceptor cell disorganized, abnormal green sensitive photoreceptor cell hypertrophic, abnormal red sensitive photoreceptor cell disorganized, abnormal red sensitive photoreceptor cell hypertrophic, abnormal retinal cone cell photoreceptor outer segment absent, abnormal retinal cone cell photoreceptor outer segment broken, abnormal retinal outer nuclear layer decreased thickness, abnormal retinal outer nuclear layer has fewer parts of type green sensitive photoreceptor cell, abnormal retinal outer nuclear layer has fewer parts of type red sensitive photoreceptor cell, abnormal
	Fig. 4		retinal outer nuclear layer apoptotic process increased process quality, abnormal retinal outer nuclear layer decreased thickness, abnormal
Engeszer et al., 2008	Fig. 1		melanocyte colorless, abnormal pigmentation disrupted, abnormal
Thummel et al., 2008	Fig. 7		photoreceptor outer segment layer tissue regeneration process quality, normal
	Fig. 8		photoreceptor outer segment layer tissue regeneration process quality, normal