| ZFIN ID: ZDB-EXP-210511-10 |
Experiment Conditions Description: chemical treatment by diet: exopolysaccharide, chemical treatment by injection: lificiguat, high fat
| chemical treatment by diet: exopolysaccharide |
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| Name: | chemical treatment by diet |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the diet. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000239] |
| Name: | exopolysaccharide |
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| Synonyms: | exopolysaccharides, extracellular polymeric substance, extracellular polymeric substances |
| Definition: | A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment. |
| Ontology: | ChEBI [CHEBI:72813] ( EBI ) |
| chemical treatment by injection: lificiguat |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | lificiguat |
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| Synonyms: | 1-benzyl-3-(5-hydroxymethyl-2-furyl)indazole, 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole, [5-(1-benzyl-1H-indazol-3-yl)-2-furyl]methanol, lificiguat, lificiguatum, YC-1 |
| Definition: | A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation. |
| Ontology: | ChEBI [CHEBI:142430] ( EBI ) |
| high fat |
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| Name: | high fat |
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| Synonyms: | |
| Definition: | Fat content condition in which the amount of fat in the diet is elevated. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000122] |
| Publication: | Zhang et al., 2019 |
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