| ZFIN ID: ZDB-EXP-181031-7 |
Experiment Conditions Description: chemical treatment: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
| chemical treatment: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide |
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| Synonyms: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, 4-dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide, D237, histone deacetylase inhibitor III, M-344, M344, N-hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide |
| Definition: | A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines. |
| Ontology: | ChEBI [CHEBI:125562] ( EBI ) |
| Publication: | Babu et al., 2018 |
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