Search Ontology:
ChEBI

4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide

Term ID
CHEBI:125562
Synonyms
  • 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
  • 4-dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide
  • D237
  • histone deacetylase inhibitor III
  • M-344
  • M344
  • N-hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide
Definition
A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Phenotype where environments contain 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Phenotype modified by environments containing 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Human Disease / Model Data
Citations
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