ZFIN Publication List

ZFIN ID: ZDB-ATB-090826-2

CITATIONS (78 total)

Antibody Name: Ab1-mef2

Allanki, S., Strilic, B., Scheinberger, L., Onderwater, Y.L., Marks, A., Günther, S., Preussner, J., Kikhi, K., Looso, M., Stainier, D.Y.R., Reischauer, S. (2021) Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration. Science advances. 7:eabg6497

Beauchemin, M., Smith, A., Yin, V.P. (2015) Dynamic microRNA-101a and Fosab expression controls zebrafish heart regeneration. Development (Cambridge, England). 142:4026-37

Ben-Yair, R., Butty, V.L., Busby, M., Qiu, Y., Levine, S.S., Goren, A., Boyer, L.A., Burns, C.G., Burns, C.E. (2019) H3K27me3-mediated silencing of structural genes is required for zebrafish heart regeneration. Development (Cambridge, England). 146(19):

Bertozzi, A., Wu, C.C., Hans, S., Brand, M., Weidinger, G. (2021) Wnt/β-catenin signaling acts cell-autonomously to promote cardiomyocyte regeneration in the zebrafish heart. Developmental Biology. 481:226-237

Bertozzi, A., Wu, C.C., Nguyen, P.D., Vasudevarao, M.D., Mulaw, M.A., Koopman, C.D., de Boer, T.P., Bakkers, J., Weidinger, G. (2020) Is zebrafish heart regeneration "complete"? Lineage-restricted cardiomyocytes proliferate to pre-injury numbers but some fail to differentiate in fibrotic hearts. Developmental Biology. 471:106-118

Bertuzzi, M., Chang, W., Ampatzis, K. (2018) Adult spinal motoneurons change their neurotransmitter phenotype to control locomotion. Proceedings of the National Academy of Sciences of the United States of America. 115(42):E9926-E9933

Bise, T., de Preux Charles, A.S., Jaźwińska, A. (2019) Ciliary neurotrophic factor stimulates cardioprotection and the proliferative activity in the adult zebrafish heart. NPJ Regenerative medicine. 4:2

Bonnet, A., Lambert, G., Ernest, S., Dutrieux, F.X., Coulpier, F., Lemoine, S., Lobbardi, R., Rosa, F.M. (2017) Quaking RNA-Binding Proteins Control Early Myofibril Formation by Modulating Tropomyosin. Developmental Cell. 42(5):527-541.e4

Bühler, A., Gahr, B.M., Park, D.D., Bertozzi, A., Boos, A., Dalvoy, M., Pott, A., Oswald, F., Kovall, R.A., Kühn, B., Weidinger, G., Rottbauer, W., Just, S. (2021) Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish. PLoS Genetics. 17:e1009890

Cao, J., Navis, A., Cox, B.D., Dickson, A.L., Gemberling, M., Karra, R., Bagnat, M., Poss, K.D. (2016) Single epicardial cell transcriptome sequencing identifies Caveolin-1 as an essential factor in zebrafish heart regeneration. Development (Cambridge, England). 143(2):232-43

Chablais, F., Veit, J., Rainer, G., and Jazwinska, A. (2011) The zebrafish heart regenerates after cryoinjury-induced myocardial infarction. BMC Developmental Biology. 11:21

Chang, W., Pedroni, A., Bertuzzi, M., Kizil, C., Simon, A., Ampatzis, K. (2021) Locomotion dependent neuron-glia interactions control neurogenesis and regeneration in the adult zebrafish spinal cord. Nature communications. 12:4857

Cheng, F., Miao, L., Wu, Q., Gong, X., Xiong, J., Zhang, J. (2016) Vinculin b deficiency causes epicardial hyperplasia and coronary vessel disorganization in zebrafish. Development (Cambridge, England). 143(19):3522-3531

de Bakker, D.E.M., Bouwman, M., Dronkers, E., Simões, F.C., Riley, P.R., Goumans, M.J., Smits, A.M., Bakkers, J. (2021) Prrx1b restricts fibrosis and promotes Nrg1-dependent cardiomyocyte proliferation during zebrafish heart regeneration. Development (Cambridge, England). 148(19):

de Preux Charles, A.S., Bise, T., Baier, F., Sallin, P., Jaźwińska, A. (2016) Preconditioning boosts regenerative programmes in the adult zebrafish heart. Open Biology. 6(7)

Devakanmalai, G.S., Zumrut, H.E., and Ozbudak, E.M. (2013) Cited3 activates Mef2c to control muscle cell differentiation and survival. Biology Open. 2(5):505-514

Diao, J., Wang, H., Chang, N., Zhou, X.H., Zhu, X., Wang, J., Xiong, J.W. (2015) PEG-PLA Nanoparticles facilitate siRNA knockdown in adult zebrafish heart. Developmental Biology. 406(2):196-202

Ding, Y., Liu, W., Deng, Y., Jomok, B., Yang, J., Huang, W., Clark, K.J., Zhong, T., Lin, X., Ekker, S.C., and Xu, X. (2013) Trapping Cardiac Recessive Mutants via Expression-based Insertional Mutagenesis Screening. Circulation research. 112(4):606-617

El-Sammak, H., Yang, B., Guenther, S., Chen, W., Marín-Juez, R., Stainier, D.Y.R. (2022) A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. Circulation research. 130(7):1014-1029

Ernens, I., Lumley, A.I., Devaux, Y. (2018) Restoration of cardiac function after anaemia-induced heart failure in zebrafish. Journal of Molecular and Cellular Cardiology. 121:223-232

Fang, Y., Lai, K.S., She, P., Sun, J., Tao, W., Zhong, T.P. (2020) Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion. Frontiers in cell and developmental biology. 8:738

FitzSimons, M., Beauchemin, M., Smith, A.M., Stroh, E.G., Kelpsch, D.J., Lamb, M.C., Tootle, T.L., Yin, V.P. (2020) Cardiac injury modulates critical components of prostaglandin E₂ signaling during zebrafish heart regeneration. Scientific Reports. 10:3095

Flinn, M.A., Jeffery, B.E., O'Meara, C.C., Link, B.A. (2018) Yap is Required for Scar Formation but not Myocyte Proliferation During Heart Regeneration in Zebrafish. Cardiovascular research. 115(3):570-577

Ganassi, M., Badodi, S., Polacchini, A., Baruffaldi, F., Battini, R., Hughes, S.M., Hinits, Y., Molinari, S. (2014) Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb. Biochimica et biophysica acta. Gene regulatory mechanisms. 1839(7):559-70

Gemberling, M., Karra, R., Dickson, A.L., Poss, K.D. (2015) Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish. eLIFE. 4

González-Rosa, J.M., Sharpe, M., Field, D., Soonpaa, M.H., Field, L.J., Burns, C.E., Burns, C.G. (2018) Myocardial Polyploidization Creates a Barrier to Heart Regeneration in Zebrafish. Developmental Cell. 44:433-446.e7

Grivas, D., González-Rajal, Á., de la Pompa, J.L. (2021) Midkine-a Regulates the Formation of a Fibrotic Scar During Zebrafish Heart Regeneration. Frontiers in cell and developmental biology. 9:669439

Grivas, D., González-Rajal, Á., Guerrero Rodríguez, C., Garcia, R., de la Pompa, J.L. (2020) Loss of Caveolin-1 and caveolae leads to increased cardiac cell stiffness and functional decline of the adult zebrafish heart. Scientific Reports. 10:12816

Han, P., Zhou, X.H., Chang, N., Xiao, C.L., Yan, S., Ren, H., Yang, X.Z., Zhang, M.L., Wu, Q., Tang, B., Diao, J.P., Zhu, X., Zhang, C., Li, C.Y., Cheng, H., Xiong, J.W. (2014) Hydrogen peroxide primes heart regeneration with a derepression mechanism. Cell Research. 24(9):1091-107

Han, Y., Chen, A., Umansky, K.B., Oonk, K.A., Choi, W.Y., Dickson, A.L., Ou, J., Cigliola, V., Yifa, O., Cao, J., Tornini, V.A., Cox, B.D., Tzahor, E., Poss, K.D. (2019) Vitamin D Stimulates Cardiomyocyte Proliferation and Controls Organ Size and Regeneration in Zebrafish. Developmental Cell. 48(6):853-863.e5

Harrison, M.R., Feng, X., Mo, G., Aguayo, A., Villafuerte, J., Yoshida, T., Pearson, C.A., Schulte-Merker, S., Lien, C.L. (2019) Late developing cardiac lymphatic vasculature supports adult zebrafish heart function and regeneration. eLIFE. 8:

Hinits, Y., and Hughes, S.M. (2007) Mef2s are required for thick filament formation in nascent muscle fibres. Development (Cambridge, England). 134(13):2511-2519

Hinits, Y., Osborn, D.P., and Hughes, S.M. (2009) Differential requirements for myogenic regulatory factors distinguish medial and lateral somitic, cranial and fin muscle fibre populations. Development (Cambridge, England). 136(3):403-414

Hinits, Y., Pan, L., Walker, C., Dowd, J., Moens, C.B., and Hughes, S.M. (2012) Zebrafish Mef2ca and Mef2cb are essential for both first and second heart field cardiomyocyte differentiation. Developmental Biology. 369(2):199-210

Honkoop, H., de Bakker, D.E., Aharonov, A., Kruse, F., Shakked, A., Nguyen, P.D., de Heus, C., Garric, L., Muraro, M.J., Shoffner, A., Tessadori, F., Peterson, J.C., Noort, W., Bertozzi, A., Weidinger, G., Posthuma, G., Grun, D., van der Laarse, W.J., Klumperman, J., Jaspers, R.T., Poss, K.D., van Oudenaarden, A., Tzahor, E., Bakkers, J. (2019) Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart. eLIFE. 8:

Hu, B., Lelek, S., Spanjaard, B., El-Sammak, H., Simões, M.G., Mintcheva, J., Aliee, H., Schäfer, R., Meyer, A.M., Theis, F., Stainier, D.Y.R., Panáková, D., Junker, J.P. (2022) Origin and function of activated fibroblast states during zebrafish heart regeneration. Nature Genetics. 54(8):1227-1237

Huang, W., Zhang, R., and Xu, X. (2009) Myofibrillogenesis in the Developing Zebrafish Heart: A Functional Study of tnnt2. Developmental Biology. 331(2):237-249

Itou, J., Kawakami, H., Burgoyne, T., and Kawakami, Y. (2012) Life-long preservation of the regenerative capacity in the fin and heart in zebrafish. Biology Open. 1(8):739-746

Itou, J., Oishi, I., Kawakami, H., Glass, T.J., Richter, J., Johnson, A., Lund, T.C., and Kawakami, Y. (2012) Migration of cardiomyocytes is essential for heart regeneration in zebrafish. Development (Cambridge, England). 139(22):4133-4142

Jean, M.J., Deverteuil, P., Lopez, N.H., Tapia, J.D., and Schoffstall, B. (2012) Adult zebrafish hearts efficiently compensate for excessive forced overload cardiac stress with hyperplastic cardiomegaly. BioResearch Open Access. 1(2):88-91

Just, S., Raphel, L., Berger, I.M., Bühler, A., Keßler, M., Rottbauer, W. (2016) Tbx20 Is an Essential Regulator of Embryonic Heart Growth in Zebrafish. PLoS One. 11:e0167306

Kinoshita, H., Ohgane, N., Fujino, Y., Yabe, T., Ovara, H., Yokota, D., Izuka, A., Kage, D., Yamasu, K., Takada, S., Kawamura, A. (2018) Functional roles of the Ripply-mediated suppression of segmentation gene expression at the anterior presomitic mesoderm in zebrafish. Mechanisms of Development. 152:21-31

Koth, J., Wang, X., Killen, A.C., Stockdale, W.T., Potts, H.G., Jefferson, A., Bonkhofer, F., Riley, P.R., Patient, R.K., Göttgens, B., Mommersteeg, M.T.M. (2020) Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration. Development (Cambridge, England). 147(8)

Kula-Alwar, D., Marber, M.S., Hughes, S.M., Hinits, Y. (2020) Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle. Developmental Biology. 470:95-107

Magadum, A., Ding, Y., He, L., Kim, T., Vasudevarao, M.D., Long, Q., Yang, K., Wickramasinghe, N., Renikunta, H.V., Dubois, N., Weidinger, G., Yang, Q., Engel, F.B. (2017) Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair. Cell Research. 27(8):1002-1019

Marín-Juez, R., El-Sammak, H., Helker, C.S.M., Kamezaki, A., Mullapuli, S.T., Bibli, S.I., Foglia, M.J., Fleming, I., Poss, K.D., Stainier, D.Y.R. (2019) Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation. Developmental Cell. 51:503-515.e4

Miklas, J.W., Levy, S., Hofsteen, P., Mex, D.I., Clark, E., Muster, J., Robitaille, A.M., Sivaram, G., Abell, L., Goodson, J.M., Pranoto, I., Madan, A., Chin, M.T., Tian, R., Murry, C.E., Moon, R.T., Wang, Y., Ruohola-Baker, H. (2021) Amino acid primed mTOR activity is essential for heart regeneration. iScience. 25:103574

Missinato, M.A., Saydmohammed, M., Zuppo, D.A., Rao, K.S., Opie, G.W., Kühn, B., Tsang, M. (2018) Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration. Development (Cambridge, England). 145(5)

Missinato, M.A., Tobita, K., Romano, N., Carroll, J.A., Tsang, M. (2015) Extracellular component hyaluronic acid and its receptor Hmmr are required for epicardial EMT during heart regeneration. Cardiovascular research. 107(4):487-98

Missinato, M.A., Zuppo, D.A., Watkins, S.C., Bruchez, M.P., Tsang, M. (2021) Zebrafish heart regenerates after chemoptogenetic cardiomyocyte depletion. Developmental Dynamics : an official publication of the American Association of Anatomists. 250(7):986-1000

Murphy, L.B., Santos-Ledo, A., Dhanaseelan, T., Eley, L., Burns, D., Henderson, D.J., Chaudhry, B. (2021) Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish. Disease models & mechanisms. 14(7):

Münch, J., Grivas, D., González-Rajal, Á., Torregrosa-Carrión, R., de la Pompa, J.L. (2017) Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart.. Development (Cambridge, England). 144(8):1425-1440

Ogawa, M., Geng, F.S., Humphreys, D.T., Kristianto, E., Sheng, D.Z., Hui, S.P., Zhang, Y., Sugimoto, K., Nakayama, M., Zheng, D., Hesselson, D., Hodson, M.P., Bogdanovic, O., Kikuchi, K. (2021) Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish. Science (New York, N.Y.). 372:201-205

Paavola, J., Alakoski, T., Ulvila, J., Kilpiö, T., Sirén, J., Perttunen, S., Narumanchi, S., Wang, H., Lin, R., Porvari, K., Junttila, J., Huikuri, H., Immonen, K., Lakkisto, P., Magga, J., Tikkanen, I., Kerkelä, R. (2020) Vezf1 regulates cardiac structure and contractile function. EBioMedicine. 51:102608

Patterson, M., Barske, L., Van Handel, B., Rau, C.D., Gan, P., Sharma, A., Parikh, S., Denholtz, M., Huang, Y., Yamaguchi, Y., Shen, H., Allayee, H., Crump, J.G., Force, T.I., Lien, C.L., Makita, T., Lusis, A.J., Kumar, S.R., Sucov, H.M. (2017) Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nature Genetics. 49(9):1346-1353

Patterson, S.E., Bird, N.C., and Devoto, S.H. (2010) BMP regulation of myogenesis in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 239(3):806-817

Peng, X., Fan, S., Tan, J., Zeng, Z., Su, M., Zhang, Y., Yang, M., Xia, L., Fan, X., Cai, W., Tang, W.H. (2020) Wnt2bb Induces Cardiomyocyte Proliferation in Zebrafish Hearts via the jnk1/c-jun/creb1 Pathway. Frontiers in cell and developmental biology. 8:323

Peng, X., Lai, K.S., She, P., Kang, J., Wang, T., Li, G., Zhou, Y., Sun, J., Jin, D., Xu, X., Liao, L., Liu, J., Lee, E., Poss, K.D., Zhong, T.P. (2020) Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration. Journal of molecular cell biology. 13(1):41-58

Rochon, E., Missinato, M.A., Xue, J., Tejero, J., Tsang, M., Gladwin, M.T., Corti, P. (2019) Nitrite improves heart regeneration in zebrafish. Antioxidants & redox signaling. 32(6):363-377

Rovira, M., Borràs, D.M., Marques, I.J., Puig, C., Planas, J.V. (2018) Physiological Responses to Swimming-Induced Exercise in the Adult Zebrafish Regenerating Heart. Frontiers in Physiology. 9:1362

Saera-Vila, A., Kasprick, D.S., Junttila, T.L., Grzegorski, S.J., Louie, K.W., Chiari, E.F., Kish, P.E., Kahana, A. (2015) Myocyte Dedifferentiation Drives Extraocular Muscle Regeneration in Adult Zebrafish. Investigative ophthalmology & visual science. 56:4977-4993

She, P., Zhang, H., Peng, X., Sun, J., Gao, B., Zhou, Y., Zhu, X., Hu, X., Lai, K.S., Wong, J., Zhou, B., Wang, L., Zhong, T.P. (2020) The Gridlock transcriptional repressor impedes vertebrate heart regeneration by restricting expression of lysine methyltransferase. Development (Cambridge, England). 147(18):

Smith, A.M., Maguire-Nguyen, K.K., Rando, T.A., Zasloff, M.A., Strange, K.B., Yin, V.P. (2017) The protein tyrosine phosphatase 1B inhibitor MSI-1436 stimulates regeneration of heart and multiple other tissues. NPJ Regenerative medicine. 2:4

Stockdale, W.T., Lemieux, M.E., Killen, A.C., Zhao, J., Hu, Z., Riepsaame, J., Hamilton, N., Kudoh, T., Riley, P.R., van Aerle, R., Yamamoto, Y., Mommersteeg, M.T.M. (2018) Heart Regeneration in the Mexican Cavefish. Cell Reports. 25:1997-2007.e7

Sun, J., She, P., Liu, X., Gao, B., Jin, D., Zhong, T.P. (2020) Disruption of Abcc6 Transporter in Zebrafish Causes Ocular Calcification and Cardiac Fibrosis. International Journal of Molecular Sciences. 22(1):

Sánchez-Iranzo, H., Galardi-Castilla, M., Sanz-Morejón, A., González-Rosa, J.M., Costa, R., Ernst, A., Sainz de Aja, J., Langa, X., Mercader, N. (2018) Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart. Proceedings of the National Academy of Sciences of the United States of America. 115(16):4188-4193

Tahara, N., Akiyama, R., Wang, J., Kawakami, H., Bessho, Y., Kawakami, Y. (2021) The FGF-AKT pathway is necessary for cardiomyocyte survival for heart regeneration in zebrafish. Developmental Biology. 472:30-37

Targoff, K.L., Schell, T., and Yelon, D. (2008) Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number. Developmental Biology. 322(2):314-321

Wang, J., Cao, J., Dickson, A.L., Poss, K.D. (2015) Epicardial regeneration is guided by cardiac outflow tract and Hedgehog signalling. Nature. 522(7555):226-30

Windner, S.E., Bird, N.C., Patterson, S.E., Doris, R.A., and Devoto, S.H. (2012) Fss/Tbx6 is required for central dermomyotome cell fate in zebrafish. Biology Open. 1(8):806-814

Witzel, H.R., Cheedipudi, S., Gao, R., Stainier, D.Y., Dobreva, G.D. (2017) Isl2b regulates anterior second heart field development in zebrafish. Scientific Reports. 7:41043

Wu, C.C., Kruse, F., Vasudevarao, M.D., Junker, J.P., Zebrowski, D.C., Fischer, K., Noël, E.S., Grün, D., Berezikov, E., Engel, F.B., van Oudenaarden, A., Weidinger, G., Bakkers, J. (2016) Spatially Resolved Genome-wide Transcriptional Profiling Identifies BMP Signaling as Essential Regulator of Zebrafish Cardiomyocyte Regeneration. Developmental Cell. 36(1):36-49

Xiao, C., Gao, L., Hou, Y., Xu, C., Chang, N., Wang, F., Hu, K., He, A., Luo, Y., Wang, J., Peng, J., Tang, F., Zhu, X., Xiong, J.W. (2016) Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish. Nature communications. 7:13787

Yang, J., and Xu, X. (2012) alpha-Actinin2 is required for the lateral alignment of Z discs and ventricular chamber enlargement during zebrafish cardiogenesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 26(10):4230-4242

Yogev, O., Williams, V.C., Hinits, Y., and Hughes, S.M. (2013) eIF4EBP3L acts as a gatekeeper of TORC1 in activity-dependent muscle growth by specifically regulating Mef2ca translational initiation. PLoS Biology. 11(10):e1001679

Zhang, R., Han, P., Yang, H., Ouyang, K., Lee, D., Lin, Y.F., Ocorr, K., Kang, G., Chen, J., Stainier, D.Y., Yelon, D., and Chi, N.C. (2013) In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature. 498(7455):497-501

Zhao, L., Ben-Yair, R., Burns, C.E., Burns, C.G. (2019) Endocardial Notch Signaling Promotes Cardiomyocyte Proliferation in the Regenerating Zebrafish Heart through Wnt Pathway Antagonism. Cell Reports. 26:546-554.e5

Additional Citations (1):

ZFIN Staff (2008) Antibody information from supplier. Manually curated data.