Gene

me3

ID
ZDB-GENE-041111-294
Name
malic enzyme 3, NADP(+)-dependent, mitochondrial
Symbol
me3 Nomenclature History
Previous Names
  • im:7151680
  • wu:fi43b04
  • zgc:163117 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process and pyruvate metabolic process. Predicted to be active in mitochondrion. Is expressed in pectoral fin musculature and pronephric duct. Orthologous to several human genes including ME3 (malic enzyme 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With me3 Human Ortholog
No data available
Associated With me3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR015884 Malic enzyme, conserved site
Domain IPR012301 Malic enzyme, N-terminal domain
Domain IPR012302 Malic enzyme, NAD-binding
Family IPR001891 Malic oxidoreductase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Homologous_superfamily IPR037062 Malic enzyme, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Malic enzyme, conserved site Malic enzyme, NAD-binding Malic enzyme, N-terminal domain Malic enzyme, N-terminal domain superfamily Malic oxidoreductase NAD(P)-binding domain superfamily
UniProtKB:A4QPA0 603
UniProtKB:Q58EG6 213
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations