Gene

washc5

ID
ZDB-GENE-040426-838
Name
WASH complex subunit 5
Symbol
washc5 Nomenclature History
Previous Names
  • spastic paraplegia 8 (1)
  • strumpellin (1)
  • zgc:55908 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Acts upstream of or within axonogenesis and heart contraction. Predicted to be located in early endosome. Predicted to be part of WASH complex. Predicted to be active in endosome. Human ortholog(s) of this gene implicated in Ritscher-Schinzel syndrome 1 and hereditary spastic paraplegia 8. Orthologous to human WASHC5 (WASH complex subunit 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With washc5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hereditary spastic paraplegia 8 Alliance Spastic paraplegia 8, autosomal dominant 603563
Ritscher-Schinzel syndrome 1 Alliance Ritscher-Schinzel syndrome 1 220210
Associated With washc5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR019393 WASH complex, subunit strumpellin
Domain Details Per Protein
Protein Length WASH complex, subunit strumpellin
UniProtKB:A0A0R4IF25 1021
UniProtKB:Q7ZVM1 1159
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations