Gene

espl1

ID
ZDB-GENE-030131-5188
Name
extra spindle pole bodies like 1, separase
Symbol
espl1 Nomenclature History
Previous Names
  • cds (1)
  • cease&desist (2)
  • fl55e11
  • mp:zf637-3-001691
  • separase (1)
  • wu:fl55e11 (1)
  • zf637-3-001691
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in meiotic chromosome separation. Predicted to act upstream of or within chromosome segregation and proteolysis. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Orthologous to human ESPL1 (extra spindle pole bodies like 1, separase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With espl1 Human Ortholog
No data available
Associated With espl1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR030397 SEPARIN core domain
Family IPR005314 Peptidase C50, separase
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Domain Details Per Protein
Protein Length Peptidase C50, separase SEPARIN core domain Tetratricopeptide-like helical domain superfamily
UniProtKB:E7FDD8 2182
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations