Gene

chsy1

ID
ZDB-GENE-030131-3127
Name
chondroitin sulfate synthase 1
Symbol
chsy1 Nomenclature History
Previous Names
  • chys1
  • wu:fc27h05
  • wu:fc27h06
  • zgc:64191
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Acts upstream of or within several processes, including animal organ morphogenesis; chondroitin sulfate proteoglycan biosynthetic process; and pectoral fin development. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane. Is expressed in several structures, including cranium; forerunner cell group; inner ear; optic primordium; and pectoral fin bud. Human ortholog(s) of this gene implicated in temtamy preaxial brachydactyly syndrome. Orthologous to human CHSY1 (chondroitin sulfate synthase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chsy1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
temtamy preaxial brachydactyly syndrome Alliance Temtamy preaxial brachydactyly syndrome 605282
Associated With chsy1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR008428 Chondroitin N-acetylgalactosaminyltransferase
Homologous_superfamily IPR029044 Nucleotide-diphospho-sugar transferases
Domain Details Per Protein
Protein Length Chondroitin N-acetylgalactosaminyltransferase Nucleotide-diphospho-sugar transferases
UniProtKB:Q6P296 801
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations