TALEN

TALEN1-ppp2r3a

ID

ZDB-TALEN-190415-1

Name

TALEN1-ppp2r3a

Previous Names

None

Target

ppp2r3a (1)

Target Sequence 1

5' - GCGGGGTGAACTGGCCT - 3'

Target Sequence 2

5' - GGAAGGACAAAGTCAC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ihb369	ppp2r3a
ihb370	ppp2r3a

Expression

Gene expression in Wild Types + TALEN1-ppp2r3a

No data available

Phenotype

Phenotype resulting from TALEN1-ppp2r3a

No data available

Phenotype of all Fish created by or utilizing TALEN1-ppp2r3a

Phenotype	Fish	Conditions	Figures
atrium decreased size, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 2 from Song et al., 2018
heart contraction decreased rate, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 3 from Song et al., 2018
myocardium mitochondrion swollen, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 4 from Song et al., 2018
cardiac muscle cell decreased amount, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 2 from Song et al., 2018
whole organism gata6 expression decreased amount, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 6 from Song et al., 2018
whole organism nkd2a expression increased amount, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 6 from Song et al., 2018
myocardium desmosome morphology, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 4 from Song et al., 2018
heart decreased functionality, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 3 from Song et al., 2018
cardiac ventricle increased size, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 2 from Song et al., 2018
cardiac muscle I band absent, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 4 from Song et al., 2018
myocardium Z disc irregular thickness, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 4 from Song et al., 2018
myocardium intercalated disc morphology, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 4 from Song et al., 2018
whole organism nkx2.5 expression increased amount, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 6 from Song et al., 2018
heart looping disrupted, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 5 from Song et al., 2018
whole organism gata4 expression increased amount, abnormal	ppp2r3a^{ihb369/ihb369}	standard conditions	Fig. 6 from Song et al., 2018
heart contraction decreased rate, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 3 from Song et al., 2018
cardiac muscle cell decreased amount, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 2 from Song et al., 2018
whole organism gata6 expression decreased amount, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 6 from Song et al., 2018
atrium decreased size, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 2 from Song et al., 2018
heart decreased functionality, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 3 from Song et al., 2018
whole organism nkd2a expression increased amount, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 6 from Song et al., 2018
myocardium desmosome morphology, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 4 from Song et al., 2018
myocardium mitochondrion swollen, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 4 from Song et al., 2018
cardiac muscle I band absent, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 4 from Song et al., 2018
cardiac ventricle increased size, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 2 from Song et al., 2018
myocardium Z disc irregular thickness, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 4 from Song et al., 2018
whole organism nkx2.5 expression increased amount, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 6 from Song et al., 2018
heart looping disrupted, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 5 from Song et al., 2018
myocardium intercalated disc morphology, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 4 from Song et al., 2018
whole organism gata4 expression increased amount, abnormal	ppp2r3a^{ihb370/ihb370}	standard conditions	Fig. 6 from Song et al., 2018

Citations