ZFIN ID: ZDB-GENE-070912-646
Gene Name: protein phosphatase 2, regulatory subunit B'', alpha
Gene Symbol: ppp2r3a    Nomenclature History

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Previous Name: si:dkeyp-38b6.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have protein phosphatase regulator activity. Involved in heart development. Predicted to localize to the protein phosphatase type 2A complex. Is expressed in brain; heart; liver; muscle; and pleuroperitoneal region. Orthologous to human PPP2R3A (protein phosphatase 2 regulatory subunit B''alpha).
Genome Resources: Alliance (1),  Gene:565849 (1),  Ensembl(GRCz11):ENSDARG00000077722 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb145 Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb369 Small Deletion Exon 3 Unknown TALEN
    ihb370 Small Deletion Exon 3 Unknown TALEN
    sa9325 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11938 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14576 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19761 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39836 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf747 Indel Exon 1 Unknown CRISPR
    zf748 Small Deletion Exon 1 Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ppp2r3a 1
    MO1-ppp2r3a N/A 1
    TALEN1-ppp2r3a 2
    DISEASE ASSOCIATED WITH ppp2r3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ppp2r3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process heart development (more)
    Cellular Component protein phosphatase type 2A complex (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR002048 EF-hand domain
    Homologous_superfamily IPR011992 EF-hand domain pair
    Binding_site IPR018247 EF-Hand 1, calcium-binding site
    Domain IPR041534 PP2A regulatory subunit B'', EF-hand domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ppp2r3a-202 (1)    Ensembl 3444
    ppp2r3a-203 (1)    Ensembl 5573
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ppp2r3a No data available
    MARKER RELATIONSHIPS
    ppp2r3a Contained in: [BAC] DKEYP-38B6 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005163406 (1) 5267 bp
    Genomic GenBank:BX294118 (1) 184616 bp
    Select Tool
    Polypeptide UniProtKB:E9QG28 (1) 1192 aa
    Sequence Information (all 12)
    ORTHOLOGY for ppp2r3a ( Chr: 2 )
    CITATIONS (21)