ZFIN ID: ZDB-PUB-961014-1247
Identified motoneurons and their innervation of axial muscles in the zebrafish
Westerfield, M., McMurray, J.V., and Eisen, J.S.
Date: 1986
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience 6: 2267-2277 (Journal)
Registered Authors: Eisen, Judith S., Westerfield, Monte
Keywords: none
MeSH Terms: Animals; Evoked Potentials; Fishes; Horseradish Peroxidase; Motor Neurons/anatomy & histology* (all 6) expand
PubMed: 3746409
The organization of spinal cord motoneurons and their innervation of axial (white) muscles in the zebrafish were studied. Motoneurons can be divided into 2 classes, primary and secondary, on the basis of their cell-body sizes and positions. Each side of each spinal segment contains 3 primary motoneurons that are uniquely identifiable as individuals by their stereotyped cell-body positions and peripheral branching patterns. Moreover, these motoneurons precisely innervate cell-specific subsets of contiguous muscle fibers in mutually exclusive regions of their own body segment. Individual muscle fibers receive inputs from a single primary motoneuron and, in addition, from up to 3 secondary motoneurons. The results demonstrate that the precision of innervation previously described in invertebrates is also present in some vertebrates.