PUBLICATION
Adult zebrafish as advanced models of human disease
- Authors
- White, R.M., Patton, E.E.
- ID
- ZDB-PUB-230731-46
- Date
- 2023
- Source
- Disease models & mechanisms 16(8): (Journal)
- Registered Authors
- Patton, E. Elizabeth
- Keywords
- Adult zebrafish, Disease modelling, Human disease
- MeSH Terms
-
- Adult
- Animals
- Disease Models, Animal
- Heart
- Humans
- Neoplasms*
- Social Behavior
- Zebrafish*
- PubMed
- 37522272 Full text @ Dis. Model. Mech.
Citation
White, R.M., Patton, E.E. (2023) Adult zebrafish as advanced models of human disease. Disease models & mechanisms. 16(8):.
Abstract
Modelling adult diseases to understand their aetiology and progression, and to develop new therapies, is a major challenge for medical biology. We are excited by new efforts in the zebrafish community to develop models of adult diseases that range from cancer to heart, infectious and age-related diseases, and those that relate to toxicology and complex social behaviours. Here, we discuss some of the advances in the field of zebrafish models of adult disease, and where we see opportunities and challenges ahead.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping