PUBLICATION
Resident Macrophage Lookalikes of Unexpected Origin
- Authors
- Levraud, J.P., Herbomel, P.
- ID
- ZDB-PUB-190522-7
- Date
- 2019
- Source
- Developmental Cell 49: 501-502 (Other)
- Registered Authors
- Herbomel, Philippe, Levraud, Jean-Pierre
- Keywords
- none
- MeSH Terms
-
- Zebrafish*
- Langerhans Cells*
- Ectoderm
- Animals
- Macrophages
- Epidermis
- PubMed
- 31112695 Full text @ Dev. Cell
Citation
Levraud, J.P., Herbomel, P. (2019) Resident Macrophage Lookalikes of Unexpected Origin. Developmental Cell. 49:501-502.
Abstract
In this issue of Developmental Cell, Lin et al. (2019) identify in zebrafish skin macrophage-like cells that sample the environment through transepithelial protrusions and import antigen from the water for traditional tissue-resident macrophages. Remarkably, these "metaphocytes" originate from the epidermis, challenging current assumptions about the lineage of tissue-resident macrophages.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping