PUBLICATION
GnRH-mediated olfactory and visual inputs promote mating-like behaviors in male zebrafish
- Authors
- Li, L., Wojtowicz, J.L., Malin, J.H., Huang, T., Lee, E.B., Chen, Z.
- ID
- ZDB-PUB-170323-6
- Date
- 2017
- Source
- PLoS One 12: e0174143 (Journal)
- Registered Authors
- Li, Lei
- Keywords
- Zebrafish, Olfactory receptor neurons, Swimming, Glutamate, Methionine, Retinal ganglion cells, GnRH stimulation test, Olfactory bulb
- MeSH Terms
-
- Animals
- Gonadotropin-Releasing Hormone/metabolism*
- Male
- Neurons/metabolism
- Neurons/physiology
- Olfactory Bulb/metabolism*
- Reproduction/physiology
- Sexual Behavior, Animal/physiology*
- Smell/physiology
- Zebrafish/metabolism*
- Zebrafish/physiology*
- PubMed
- 28329004 Full text @ PLoS One
Citation
Li, L., Wojtowicz, J.L., Malin, J.H., Huang, T., Lee, E.B., Chen, Z. (2017) GnRH-mediated olfactory and visual inputs promote mating-like behaviors in male zebrafish. PLoS One. 12:e0174143.
Abstract
The engagement of sexual behaviors is regulated by a number of factors which include gene expression, hormone circulation, and multi-sensory information integration. In zebrafish, when a male and a female are placed in the same container, they show mating-like behaviors regardless of whether they are kept together or separated by a net. No mating-like behaviors are observed when same-sex animals are put together. Through the olfacto-visual centrifugal pathway, activation of the terminalis nerve in the olfactory bulb increases GnRH signaling in the brain and triggers mating-like behaviors between males. In zebrafish mutants or wild-type fish in which the olfacto-visual centrifugal pathway is impaired or chemically ablated, in response to odor stimulation the mating-like behaviors between males are no longer evident. Together, the data suggest that the combination of olfactory and visual signals alter male zebrafish's mating-like behaviors via GnRH signaling.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping