ZFIN ID: ZDB-PUB-170323-6
GnRH-mediated olfactory and visual inputs promote mating-like behaviors in male zebrafish
Li, L., Wojtowicz, J.L., Malin, J.H., Huang, T., Lee, E.B., Chen, Z.
Date: 2017
Source: PLoS One   12: e0174143 (Journal)
Registered Authors: Li, Lei
Keywords: Zebrafish, Olfactory receptor neurons, Swimming, Glutamate, Methionine, Retinal ganglion cells, GnRH stimulation test, Olfactory bulb
MeSH Terms:
  • Animals
  • Gonadotropin-Releasing Hormone/metabolism*
  • Male
  • Neurons/metabolism
  • Neurons/physiology
  • Olfactory Bulb/metabolism*
  • Reproduction/physiology
  • Sexual Behavior, Animal/physiology*
  • Smell/physiology
  • Zebrafish/metabolism*
  • Zebrafish/physiology*
PubMed: 28329004 Full text @ PLoS One
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ABSTRACT
The engagement of sexual behaviors is regulated by a number of factors which include gene expression, hormone circulation, and multi-sensory information integration. In zebrafish, when a male and a female are placed in the same container, they show mating-like behaviors regardless of whether they are kept together or separated by a net. No mating-like behaviors are observed when same-sex animals are put together. Through the olfacto-visual centrifugal pathway, activation of the terminalis nerve in the olfactory bulb increases GnRH signaling in the brain and triggers mating-like behaviors between males. In zebrafish mutants or wild-type fish in which the olfacto-visual centrifugal pathway is impaired or chemically ablated, in response to odor stimulation the mating-like behaviors between males are no longer evident. Together, the data suggest that the combination of olfactory and visual signals alter male zebrafish's mating-like behaviors via GnRH signaling.
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