PUBLICATION
Cell behaviors and dynamics during angiogenesis
- Authors
- Betz, C., Lenard, A., Belting, H.G., Affolter, M.
- ID
- ZDB-PUB-160707-2
- Date
- 2016
- Source
- Development (Cambridge, England) 143: 2249-60 (Review)
- Registered Authors
- Affolter, Markus, Belting, Heinz-Georg Paul (Henry), Lenard, Anna
- Keywords
- Anastomosis, Angiogenesis, Endothelial cells, Live imaging, Pruning, Sprouting, Vegf, Zebrafish
- MeSH Terms
-
- Cell Fusion
- Models, Biological
- Endothelial Cells/cytology*
- Endothelial Cells/metabolism
- Humans
- Morphogenesis
- Animals
- Signal Transduction
- Neovascularization, Physiologic*
- PubMed
- 27381223 Full text @ Development
Citation
Betz, C., Lenard, A., Belting, H.G., Affolter, M. (2016) Cell behaviors and dynamics during angiogenesis. Development (Cambridge, England). 143:2249-60.
Abstract
Vascular networks are formed and maintained through a multitude of angiogenic processes, such as sprouting, anastomosis and pruning. Only recently has it become possible to study the behavior of the endothelial cells that contribute to these networks at a single-cell level in vivo This Review summarizes what is known about endothelial cell behavior during developmental angiogenesis, focusing on the morphogenetic changes that these cells undergo.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping