ZFIN ID: ZDB-PUB-160707-2
Cell behaviors and dynamics during angiogenesis
Betz, C., Lenard, A., Belting, H.G., Affolter, M.
Date: 2016
Source: Development (Cambridge, England)   143: 2249-60 (Review)
Registered Authors: Affolter, Markus, Belting, Heinz-Georg Paul (Henry), Lenard, Anna
Keywords: Anastomosis, Angiogenesis, Endothelial cells, Live imaging, Pruning, Sprouting, Vegf, Zebrafish
MeSH Terms:
  • Animals
  • Cell Fusion
  • Endothelial Cells/cytology*
  • Endothelial Cells/metabolism
  • Humans
  • Models, Biological
  • Morphogenesis
  • Neovascularization, Physiologic*
  • Signal Transduction
PubMed: 27381223 Full text @ Development
Vascular networks are formed and maintained through a multitude of angiogenic processes, such as sprouting, anastomosis and pruning. Only recently has it become possible to study the behavior of the endothelial cells that contribute to these networks at a single-cell level in vivo This Review summarizes what is known about endothelial cell behavior during developmental angiogenesis, focusing on the morphogenetic changes that these cells undergo.