ZFIN ID: ZDB-PUB-131010-4
Zebrafish-based small molecule screens for novel cardiovascular drugs
Novodvorsky, P., da Costa, M.M.J., and Chico, T.J.A.
Date: 2013
Source: Drug Discovery Today: Technologies   10(1): e109-e114 (Review)
Registered Authors: Chico, Tim J.
Keywords: none
MeSH Terms:
  • Animals
  • Cardiovascular Agents*
  • Drug Evaluation, Preclinical
  • High-Throughput Screening Assays*
  • Zebrafish*
PubMed: 24050238 Full text @ Drug Discov. Today Technol.

The zebrafish is increasingly being adopted as an in vivo model of high throughput drug screening. In this brief review we outline the advantages and disadvantages of this approach and summarize recent screens that have attempted to identify novel small molecules with activity on the cardiovascular system.