PUBLICATION
The genetics of outer segment morphogenesis in zebrafish
- Authors
- Reynolds, A.L., Blacque, O.E., and Kennedy, B.N.
- ID
- ZDB-PUB-120105-90
- Date
- 2012
- Source
- Advances in experimental medicine and biology 723: 431-441 (Chapter)
- Registered Authors
- Kennedy, Breandan N.
- Keywords
- zebrafish, photoreceptor, outer segment, mutants, blindness, intraflagellar transport, phototransduction
- MeSH Terms
-
- Animals
- Blindness/genetics*
- Blindness/physiopathology*
- Disease Models, Animal*
- Morphogenesis/genetics
- Photoreceptor Cells, Vertebrate/physiology*
- Retinal Photoreceptor Cell Outer Segment/physiology*
- Vision, Ocular/genetics
- Zebrafish/genetics*
- PubMed
- 22183362 Full text @ Adv. Exp. Med. Biol.
Citation
Reynolds, A.L., Blacque, O.E., and Kennedy, B.N. (2012) The genetics of outer segment morphogenesis in zebrafish. Advances in experimental medicine and biology. 723:431-441.
Abstract
Appropriate outer segment (OS) morphogenesis is necessary for normal visual function. Thirty-three zebrafish mutants with OS morphogenesis defects have been reported. We describe here the phenotypes and potential mechanisms by which these mutant loci cause OS dysmorphogenesis.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping