ZFIN ID: ZDB-PUB-100322-15
Fishing for age-related visual system mutants: behavioral screening of retinal degeneration genes in zebrafish
Li, L., Li, Y., Chen, D., Shao, J., Li, X., and Xu, C.
Date: 2010
Source: Current aging science   3(1): 43-45 (Review)
Registered Authors: Li, Lei, Li, Xin, Li, Yuhao
Keywords: none
MeSH Terms:
  • Aging/genetics*
  • Animals
  • Behavior, Animal/physiology
  • Genetic Testing/methods
  • Male
  • Models, Animal
  • Mutation/genetics
  • Retinal Degeneration/genetics*
  • Retinal Degeneration/physiopathology
  • Zebrafish/genetics*
PubMed: 20298169 Full text @ Curr. Aging Sci.
The zebrafish (Danio rerio) has recently become a mainstream model system for genetic studies of human diseases, such as neurological degenerative diseases, heart diseases, immuno-system disorders, etc. In this article, we will review some recent findings of the usefulness of zebrafish as a model vertebrate for behavioral screening of mutations in vertebrate visual system, for example, genes involved in age-related retinal degeneration.