ZFIN ID: ZDB-PUB-091016-3
Evolution of the growth hormone-prolactin-somatolactin system in relation to vertebrate tetraploidizations
Ocampo Daza, D., Sundström, G., Larsson, T.A., and Larhammar, D.
Date: 2009
Source: Annals of the New York Academy of Sciences   1163: 491-493 (Journal)
Registered Authors: Larhammar, Dan, Larsson, Tomas A., Sundström, Görel
Keywords: growth hormone, growth hormone receptor, prolactin, prolactin receptor, somatolactin, somatolactin receptor, gene duplication, tetraploidization
MeSH Terms:
  • Animals
  • Chromosomes/genetics
  • Evolution, Molecular*
  • Humans
  • Phylogeny*
  • Pituitary Hormones/classification*
  • Pituitary Hormones/genetics*
  • Ploidies*
  • Vertebrates/classification*
  • Vertebrates/genetics*
PubMed: 19456396 Full text @ Ann N Y Acad Sci
Gene sequences from several species representing major vertebrate groups were used to create phylogenetic trees for the growth hormone family of peptide hormones as well as the growth hormone receptor family. These analyses show that both the peptide and receptor families were formed through local duplications in early vertebrate evolution and chromosome duplications.