PUBLICATION

Zebrafish Pancreas Development

Authors
Tiso, N., Moro, E., and Argenton, F.
ID
ZDB-PUB-090601-17
Date
2009
Source
Molecular and Cellular Endocrinology   312(1-2): 24-30 (Review)
Registered Authors
Argenton, Francesco, Moro, Enrico, Tiso, Natascia
Keywords
none
MeSH Terms
  • Animals
  • Cell Differentiation
  • Genomics/methods
  • Models, Animal*
  • Morphogenesis
  • Pancreas/embryology*
  • Pancreas/growth & development
  • Pancreas/physiology
  • Regeneration
  • Whole Body Imaging/methods
  • Zebrafish/embryology*
  • Zebrafish/genetics
  • Zebrafish/growth & development
PubMed
19477220 Full text @ Mol. Cell. Endocrinol.
Abstract
An accurate understanding of the molecular events governing pancreas development can have an impact on clinical medicine related to diabetes, obesity and pancreatic cancer, diseases with a high impact in public health. Until 1996, the main animal models in which pancreas formation and differentiation could be studied were mouse and, for some instances related to early development, chicken and Xenopus. Zebrafish has penetrated this field very rapidly offering a new model of investigation; by joining functional genomics, genetics and in vivo whole mount visualization, Danio rerio has allowed large scale and fine multidimensional analysis of gene functions during pancreas formation and differentiation.
Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Errata and Notes