Yoder, J.A., Nielsen, M.E., Amemiya, C.T., and Litman, G.W. (2002) Zebrafish as an immunological model system. Microbes and infection. 4(14):1469-1478.
Two decades of research have established the zebrafish (Danio rerio) as a significant model system for studying vertebrate development and gene structure-function relationships. Recent advances in mutation screening, the creation of genomic resources, including the Zebrafish Genome Project and the development of efficient transgenesis procedures, make this model increasingly attractive for immunological study.