ZFIN ID: ZDB-PUB-030116-5
Zebrafish as an immunological model system
Yoder, J.A., Nielsen, M.E., Amemiya, C.T., and Litman, G.W.
Date: 2002
Source: Microbes and infection 4(14): 1469-1478 (Journal)
Registered Authors: Amemiya, Chris, Litman, Gary W., Yoder, Jeffrey A.
Keywords: none
MeSH Terms:
  • Animals
  • Fish Diseases/immunology
  • Immunity, Active/genetics
  • Immunity, Innate/physiology
  • Killer Cells, Natural/immunology
  • Models, Animal*
  • Models, Immunological*
  • Mutagenesis
  • Transgenes
  • Zebrafish/genetics
  • Zebrafish/immunology*
PubMed: 12475637 Full text @ Microbes Infect.
Two decades of research have established the zebrafish (Danio rerio) as a significant model system for studying vertebrate development and gene structure-function relationships. Recent advances in mutation screening, the creation of genomic resources, including the Zebrafish Genome Project and the development of efficient transgenesis procedures, make this model increasingly attractive for immunological study.