ZFIN ID: ZDB-PERS-990302-51
Yoder, Jeffrey A.
Email: Jeff_Yoder@ncsu.edu
URL: http://www4.ncsu.edu/~jayoder/
Affiliation: Yoder Lab
Address: Department of Molecular Biomedical Sciences Center for Comparative Medicine and Translational Research College of Veterinary Medicine North Carolina State University 1060 William Moore Drive Raleigh, NC 27607-4065 USA
Country: United States
Phone: (919)-515-7406
Fax: (919) 513-7301

1. Identification and characterization of immune related genes in zebrafish.

2. Evolution of multi-gene families encoding innate immune-related receptors and MHC.

3. Intraspecific polymorphic, haplotypic and gene content variation.

Phelps, D.W., Fletcher, A.A., Rodriguez-Nunez, I., Balik-Meisner, M.R., Tokarz, D.A., Reif, D.M., Germolec, D.R., Yoder, J.A. (2020) In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish. Journal of immunotoxicology. 17:94-104
Allen, T.A., Asad, D., Amu, E., Hensley, M.T., Cores, J., Vandergriff, A., Tang, J., Dinh, P.U., Shen, D., Qiao, L., Su, T., Hu, S., Liang, H., Shive, H., Harrell, E., Campbell, C., Peng, X., Yoder, J.A., Cheng, K. (2019) Circulating tumor cells exit circulation while maintaining multicellularity augmenting metastatic potential. Journal of Cell Science. 132(17):
Tokarz, D.A., Heffelfinger, A.K., Jima, D.D., Gerlach, J., Shah, R.N., Rodriguez-Nunez, I., Kortum, A.N., Fletcher, A.A., Nordone, S.K., Law, J.M., Heber, S., Yoder, J.A. (2017) Disruption of Trim9 function abrogates macrophage motility in vivo. Journal of Leukocyte Biology. 102(6):1371-1380
Chernyavskaya, Y., Mudbhary, R., Tokarz, D., Jacob, V., Gopinath, S., Zhang, C., Sun, X., Wang, S., Magnani, E., Madakashira, B.P., Yoder, J.A., Hoshida, Y., Sadler, K.C. (2017) Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling. Development (Cambridge, England). 144(16):2925-2939
Sullivan, C., Lage, C.R., Yoder, J.A., Postlethwait, J.H., Kim, C.H. (2017) Evolutionary divergence of the vertebrate TNFAIP8 gene family: Applying the spotted gar orthology bridge to understand ohnolog loss in teleosts. PLoS One. 12:e0179517
Allen, T.A., Gracieux, D., Talib, M., Tokarz, D.A., Hensley, M.T., Cores, J., Vandergriff, A., Tang, J., de Andrade, J.B., Dinh, P.U., Yoder, J.A., Cheng, K. (2017) Angiopellosis as an Alternative Mechanism of Cell Extravasation. Stem cells (Dayton, Ohio). 35(1):170-180
Tucker, M.B., MacKenzie, S.H., Maciag, J.J., Ackerman, H.D., Swartz, P., Yoder, J.A., Hamilton, P.T., Clark, A.C. (2016) Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish. Protein science : a publication of the Protein Society. 25(11):2076-2088
McConnell, S.C., Hernandez, K.M., Wcisel, D.J., Kettleborough, R.N., Stemple, D.L., Yoder, J.A., Andrade, J., de Jong, J.L. (2016) Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution. Proceedings of the National Academy of Sciences of the United States of America. 113(34):E5014-23
Wcisel, D.J., Yoder, J.A. (2016) The confounding complexity of innate immune receptors within and between teleost species. Fish & shellfish immunology. 53:24-34
Moore, F.E., Garcia, E.G., Lobbardi, R., Jain, E., Tang, Q., Moore, J.C., Cortes, M., Molodtsov, A., Kasheta, M., Luo, C.C., Garcia, A.J., Mylvaganam, R., Yoder, J.A., Blackburn, J.S., Sadreyev, R.I., Ceol, C.J., North, T.E., Langenau, D.M. (2016) Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish. The Journal of experimental medicine. 213(6):979-92
Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
Rodriguez-Nunez, I., Wcisel, D.J., Litman, R.T., Litman, G.W., Yoder, J.A. (2016) The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes. Immunogenetics. 68(4):295-312
Yoder, J.A. (2014) Preface to the Special Issue: Zebrafish immunity and infection models. Developmental and comparative immunology. 46(1):1-2
Rodríguez-Nunez, I., Wcisel, D.J., Litman, G.W., and Yoder, J.A. (2014) Multigene families of immunoglobulin domain-containing innate immune receptors in zebrafish: Deciphering the differences. Developmental and comparative immunology. 46(1):24-34
Dirscherl, H., McConnell, S.C., Yoder, J.A., de Jong, J.L. (2014) The MHC class I genes of zebrafish. Developmental and comparative immunology. 46(1):11-23
Kortum, A.N., Rodriguez-Nunez, I., Yang, J., Shim, J., Runft, D., O'Driscoll, M.L., Haire, R.N., Cannon, J.P., Turner, P.M., Litman, R.T., Kim, C.H., Neely, M.N., Litman, G.W., and Yoder, J.A. (2014) Differential expression and ligand binding indicate alternative functions for zebrafish polymeric immunoglobulin receptor (pIgR) and a family of pIgR-like (PIGRL) proteins. Immunogenetics. 66(4):267-279
Dirscherl, H., and Yoder, J.A. (2014) Characterization of the Z lineage Major histocompatability complex class I genes in zebrafish. Immunogenetics. 66(3):185-98
Gerstner, N. (2014) Endocytic modulation of developmental signaling during Zebrafish gastrulation. Thesis.
Gabor, K.A., Stevens, C.R., Pietraszewski, M.J., Gould, T.J., Shim, J., Yoder, J.A., Lam, S.H., Gong, Z., Hess, S.T., and Kim, C.H. (2013) Super Resolution Microscopy Reveals that Caveolin-1 Is Required for Spatial Organization of CRFB1 and Subsequent Antiviral Signaling in Zebrafish. PLoS One. 8(7):e68759
Haire, R.N., Cannon, J.P., O'Driscoll, M.L., Ostrov, D.A., Mueller, M.G., Turner, P.M., Litman, R.T., Litman, G.W., and Yoder, J.A. (2012) Genomic and functional characterization of the diverse immunoglobulin domain-containing protein (DICP) family. Genomics. 99(5):282-291
Shah, R.N., Rodriguez-Nunez, I., Eason, D.D., Haire, R.N., Bertrand, J.Y., Wittamer, V., Traver, D., Nordone, S.K., Litman, G.W., and Yoder, J.A. (2012) Development and characterization of anti-nitr9 antibodies. Advances in hematology. 2012:596925
Ott, L.E., McDowell, Z.T., Turner, P.M., Law, J.M., Adler, K.B., Yoder, J.A., and Jones, S.L. (2011) Two Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Paralogs are Required for Normal Development in Zebrafish. The Anatomical record. 294(9):1511-24
Yoder, J.A., and Litman, G.W. (2011) The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities. Immunogenetics. 63(3):123-141
Deiters, A., Garner, R.A., Lusic, H., Govan, J.M., Dush, M., Nascone-Yoder, N.M., and Yoder, J.A. (2010) Photocaged Morpholino Oligomers for the Light-Regulation of Gene Function in Zebrafish and Xenopus Embryos. Journal of the American Chemical Society. 132(44):15644-15650
Phennicie, R.T., Sullivan, M.J., Singer, J.T., Yoder, J.A., and Kim, C.H. (2010) Specific Resistance to Pseudomonas aeruginosa Infection in Zebrafish is Mediated by the Cystic Fibrosis Transmembrane Conductance Regulator. Infection and Immunity. 78(11):4542-4550
Xie, J., Yin, H., Nichols, T.D., Yoder, J.A., and Horowitz, J.M. (2010) SP2 is a maternally inherited transcription factor required for embryonic development. The Journal of biological chemistry. 285(6):4153-4164
Yoder, J.A., Turner, P.M., Wright, P.D., Wittamer, V., Bertrand, J.Y., Traver, D., and Litman, G.W. (2010) Developmental and tissue-specific expression of NITRs. Immunogenetics. 62(2):117-122
Jima, D.D., Shah, R.N., Orcutt, T.M., Joshi, D., Law, J.M., Litman, G.W., Trede, N.S., and Yoder, J.A. (2009) Enhanced transcription of complement and coagulation genes in the absence of adaptive immunity. Molecular immunology. 46(7):1505-1516
Yoder, J.A. (2009) Form, function and phylogenetics of NITRs in bony fish. Developmental and comparative immunology. 33(2):135-144
Yoder, J.A. (2008) Assessing Infection and Immunity in Zebrafish. Zebrafish. 5(3):189-191
Desai, S., Heffelfinger, A.K., Orcutt, T.M., Litman, G.W., and Yoder, J.A. (2008) The medaka novel immune-type receptor (NITR) gene clusters reveal an extraordinary degree of divergence in variable domains. BMC Evolutionary Biology. 8:177
Yoder, J.A., Cannon, J.P., Litman, R.T., Murphy, C., Freeman, J.L., and Litman, G.W. (2008) Evidence for a transposition event in a second NITR gene cluster in zebrafish. Immunogenetics. 60(5):257-265
Yoder, J.A., Orcutt, T.M., Traver, D., and Litman, G.W. (2007) Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors. Gene. 401(1-2):154-164
Wei, S., Zhou, J.M., Chen, X., Shah, R.N., Liu, J., Orcutt, T.M., Traver, D., Djeu, J.Y., Litman, G.W., and Yoder, J.A. (2007) The zebrafish activating immune receptor Nitr9 signals via Dap12. Immunogenetics. 59(10):813-821
Deiters, A., and Yoder, J.A. (2006) Conditional Transgene and Gene Targeting Methodologies in Zebrafish. Zebrafish. 3(4):415-429
Panagos, P.G., Dobrinski, K.P., Chen, X., Grant, A.W., Traver, D., Djeu, J.Y., Wei, S., and Yoder, J.A. (2006) Immune-related, lectin-like receptors are differentially expressed in the myeloid and lymphoid lineages of zebrafish. Immunogenetics. 58(1):31-40
Yoder, J.A., Litman, R.T., Mueller, M.G., Desai, S., Dobrinski, K.P., Montgomery, J.S., Buzzeo, M.P., Ota, T., Amemiya, C.T., Trede, N.S., Wei, S., Djeu, J.Y., Humphray, S., Jekosch, K., Hernandez Prada, J.A., Ostrov, D.A., and Litman, G.W. (2004) Resolution of the novel immune-type receptor gene cluster in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 101(44):15706-15711
Yoder, J.A. (2004) Investigating the morphology, function and genetics of cytotoxic cells in bony fish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 138(3):271-280
Traver, D., Herbomel, P., Patton, E.E., Murphey, R.D., Yoder, J.A., Litman, G.W., Catic, A., Amemiya, C.T., Zon, L.I., and Trede, N.S. (2003) The zebrafish as a model organism to study development of the immune system. Advances in immunology. 81:253-330
Yoder, J.A., Nielsen, M.E., Amemiya, C.T., and Litman, G.W. (2002) Zebrafish as an immunological model system. Microbes and infection. 4(14):1469-1478
Yoder, J.A., Hawke, N.A., Eason, D.D., Mueller, M.G., Davids, B.J., Gillin, F.D., and Litman, G.W. (2002) BIVM, a novel gene widely distributed among Deuterostomes, shares a core sequence with an unusual gene in Giardia lamblia. Genomics. 79(6):750-755
Mhanni, A.A., Yoder, J.A., Dubesky, C., and McGowan, R.A. (2001) Cloning and sequence analysis of a zebrafish cDNA encoding DNA (cytosine-5)-methyltransferase-1. Genesis (New York, N.Y. : 2000). 30:213-219
Yoder, J.A., Mueller, M.G., Wei, S., Corliss, B.C., Prather, D.M., Willis, T., Litman, R.T., Djeu, J.Y., and Litman, G.W. (2001) Immune-type receptor genes in zebrafish share genetic and functional properties with genes encoded by the mammalian leukocyte receptor cluster. Proceedings of the National Academy of Sciences of the United States of America. 98(12):6771-6776
Litman, G.W., Hawke, N.A., and Yoder, J.A. (2001) Novel immune-type receptor genes. Immunological reviews. 181:250-259
Yoder, J.A. and Litman, G.W. (2001) Corrigendum to: "The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13". Gene. 269(1-2):227
Yoder, J.A. and Litman, G.W. (2000) The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13. Gene. 261:5-242
Yoder, J.A., Haire, R.N., and Litman, G.W. (1999) Cloning of two zebrafish cDNAs that share domains with the MHC class II-associated invariant chain. Immunogenetics. 50:84-88

Goll, M.G., F. Kirpekar, K.A. Maggert, J.A. Yoder, C. Hsieh, X. Zhang, K.G. Golic, S.E. Jacobsen, and T.H. Bestor. 2006. Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science. 20:395-398.

Yoder, J.A., M.G. Mueller, T. Ota, K. Nichols, S.S. Ristow, G.H. Thorgaard and G.W. Litman. 2002. Cloning novel immune-type inhibitory receptors from the rainbow trout, Oncorhynchus mykiss. Immunogenetics. 54: 662-670.

Hawke, N.A., J.A. Yoder, R.N. Haire, M.G. Mueller, R.T. Litman, A.L. Miracle, T. Stuge, N. Miller and G.W. Litman. 2001. Extraordinary variation in a diversified family of immune-type receptor genes. Proc Natl Acad Sci U S A. 98: 13832-13837.

Dong, A., J.A. Yoder, X. Zhang, L. Zhou, T.H. Bestor and X.Cheng. 2001. Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denturant-resistant binding to DNA. Nucleic Acids Res. 29: 439-448.

Yoder, J.A. and G.W. Litman. 2000. Immune-type diversity in the absence of somatic rearrangement. Curr. Top. Microbiol. Immunol. 248: 271-282.

Hawke, N.A., J.A. Yoder and G.W. Litman. 1999. Expanding our understanding of immunoglobulin, T cell antigen receptor and novel immune-type receptor genes: a subset of the immunoglobulin gene superfamily. Immunogenetics. 50: 124-133.

Mertineit, C., J.A. Yoder, T. Taketo, D. Laird, J. Trasler, and T.H. Bestor. 1998. Sex-specific exons control DNA methyltransferase in mammalian germ cells. Development. 125: 889-897.

Yoder, J.A., and T.H. Bestor. 1998. A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast. Hum. Mol. Gen. 7: 279-284.

Yoder, J.A., C.P. Walsh and T.H. Bestor. 1997. Cytosine methylation and the ecology of intragenomic parasites. Trends Gen. 13: 335-340.

Yoder, J.A., N.S. Soman, G.L. Verdine and T.H. Bestor. 1997. DNA (cytosine-5) methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe. J. Mol. Biol. 270: 385-395.

Yoder, J.A., R.-W.C. Yen, P.M. Vertino, T.H Bestor and S.B. Baylin. 1996. New 5’ regions of the murine and human genes for DNA (cytosine-5)-methyltransferase. J. Biol. Chem. 271: 31092-31097.

Yoder, J.A. and T.H. Bestor. 1996. Genetic analysis of genomic methylation patterns in plants and mammals. Biol. Chem. 377: 605-610.

McKinnon, C.A., F.E. Weaver, J.A. Yoder, G. Fairbanks and D.E. Wolf. 1991. Cross-linking a maturation-dependent ram sperm plasma membrane antigen induces the acrosome reaction. Mol. Repro. & Dev. 29: 200-207.