PUBLICATION
Behavioral visual responses of wild-type and hypopigmented zebrafish
- Authors
- Ren, J.Q., McCarthy, W.R., Zhang, H., Adolph, A.R., and Li, L.
- ID
- ZDB-PUB-020130-4
- Date
- 2002
- Source
- Vision Research 42(3): 293-299 (Journal)
- Registered Authors
- Li, Lei, Ren, Jason (Qianshen)
- Keywords
- chromophore; visual sensitivity; contrast sensitivity; retina; zebrafish
- MeSH Terms
-
- Animals
- Retina/pathology
- Escape Reaction/physiology*
- Visual Perception/physiology*
- Albinism, Ocular/pathology
- Albinism, Ocular/psychology*
- Zebrafish/physiology*
- Contrast Sensitivity/physiology
- Lighting
- Melanophores/physiology
- Chromatophores/physiology*
- Dark Adaptation/physiology
- PubMed
- 11809482 Full text @ Vision Res.
Citation
Ren, J.Q., McCarthy, W.R., Zhang, H., Adolph, A.R., and Li, L. (2002) Behavioral visual responses of wild-type and hypopigmented zebrafish. Vision Research. 42(3):293-299.
Abstract
Zebrafish possess three classes of chromatophores that include iridophores, melanophores, and xanthophores. Mutations that lack one or two classes of chromatophores have been isolated or genetically constructed. Using a behavioral assay based on visually mediated escape responses, we measured the visual response of fully and partially pigmented zebrafish. In zebrafish that lack iridophores (roy mutants), the behavioral visual responses were similar to those of wild-type animals except at low contrast stimulation. In the absence of melanophores (albino mutants) or both melanophores and iridophores (ruby mutants), the behavioral visual responses were normal under moderate illumination but reduced when tested under dim or bright conditions or under low contrast stimulation. Together, the data suggest that screening pigments in the retina play a role in the regulation of behavioral visual responses and are necessary for avoiding "scatter" under bright light conditions.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping