PUBLICATION
Cloning and developmental expression of a zebrafish meis2 homeobox gene
- Authors
- Zerucha, T. and Prince, V.E.
- ID
- ZDB-PUB-010410-5
- Date
- 2001
- Source
- Mechanisms of Development 102(1-2): 247-250 (Journal)
- Registered Authors
- Prince, Victoria E., Zerucha, Ted
- Keywords
- homeobox; TALE superclass; hox; meis; hindbrain; midbrain; forebrain; cerebellum; Danio rerio
- MeSH Terms
-
- Amino Acid Sequence
- Animals
- Brain/embryology
- Central Nervous System/metabolism
- DNA, Complementary/metabolism
- Homeodomain Proteins/biosynthesis*
- Homeodomain Proteins/genetics*
- In Situ Hybridization
- Mesoderm/metabolism
- Mice
- Molecular Sequence Data
- Phylogeny
- Protein Isoforms
- Retina/embryology
- Sequence Homology, Amino Acid
- Time Factors
- Tissue Distribution
- Zebrafish
- Zebrafish Proteins*
- PubMed
- 11287203 Full text @ Mech. Dev.
Citation
Zerucha, T. and Prince, V.E. (2001) Cloning and developmental expression of a zebrafish meis2 homeobox gene. Mechanisms of Development. 102(1-2):247-250.
Abstract
We show here that a zebrafish meis2 gene homolog has a dynamic expression pattern in the developing mesoderm and central nervous system. Meis family homeodomain proteins are known to act as cofactors with other homeodomain proteins. We find expression of meis2.1 in the developing zebrafish hindbrain and somites, correlating with reported sites of zebrafish hox gene expression, as well as in presumptive cerebellum, midbrain, retina and ventral forebrain. The expression pattern shares some, but not all, features with that of murine Meis2.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping