Department of Organismal Biology and Anatomy
Division of Biological Sciences
University of Chicago
1027 East 57th Street
BIOGRAPHY AND RESEARCH INTERESTS
The broad aims of our research program are to understand how developing vertebrate embryos are regionalized along the primary (anterior to posterior) body axis. Previous work from the Prince lab has contributed to our understanding of Hox genes and hindbrain patterning, gene and genome duplications, endoderm regionalization, and pancreas development. Current work is focused on collective cell migrations: we are pursuing an NSF funded project on facial branchiomotor neuron migration and a Chicago Biomedical Consortium funded project on neural crest migration.
Gale, E., Prince, V., Lumsden, A., Clarke, J., Holder, N. and Maden, M. (1996). Late effects of retinoic acid on neural crest and aspects of rhombomere identity. Development 122, 783-793.
Prince, V. and Lumsden, A. (1994). Hoxa-2 expression in normal and transposed rhombomeres: independent regulation in the neural tube and neural crest. Development 120, 911-923.
Guthrie, S., Prince, V. and Lumsden A. (1993). Selective dispersal of rhombomere cells in orthotopic and heterotopic grafting experiments. Development 118, 527-538.