ZFIN ID: ZDB-PUB-001101-8
Genetics of heart development
Chen, J.N. and Fishman, M.C.
Date: 2000
Source: Trends in genetics : TIG   16(9): 383-388 (Review)
Registered Authors: Chen, Jau-Nian, Fishman, Mark C.
Keywords: none
MeSH Terms:
  • Animals
  • Biological Evolution
  • Body Patterning
  • Heart/embryology*
  • Heart/physiology
  • Mice
  • Morphogenesis
PubMed: 10973066 Full text @ Trends Genet.
ABSTRACT
The genes that drive heart-cell differentiation in vertebrates and Drosophila are similar, even though the Drosophila 'heart' is a simple tube and the vertebrate heart is a multichambered physiologically complex organ. Mutational analysis in mice and, as particular focus of this review, in zebrafish, reveals the additional genes brought into play to fashion these evolutionarily 'new' organotypic components.
ADDITIONAL INFORMATION No data available