|ZFIN ID: ZDB-PUB-001101-8|
Genetics of heart development
Chen, J.N. and Fishman, M.C.
|Source:||Trends in genetics : TIG 16(9): 383-388 (Review)|
|Registered Authors:||Chen, Jau-Nian, Fishman, Mark C.|
|PubMed:||10973066 Full text @ Trends Genet.|
Chen, J.N. and Fishman, M.C. (2000) Genetics of heart development. Trends in genetics : TIG. 16(9):383-388.
ABSTRACTThe genes that drive heart-cell differentiation in vertebrates and Drosophila are similar, even though the Drosophila 'heart' is a simple tube and the vertebrate heart is a multichambered physiologically complex organ. Mutational analysis in mice and, as particular focus of this review, in zebrafish, reveals the additional genes brought into play to fashion these evolutionarily 'new' organotypic components.
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