PUBLICATION

Zebrafish developmental genetics and central nervous system development

Authors
Blader, P. and Strähle, U.
ID
ZDB-PUB-000505-19
Date
2000
Source
Human molecular genetics   9(6): 945-951 (Journal)
Registered Authors
Blader, Patrick, Strähle, Uwe
Keywords
none
MeSH Terms
  • Animals
  • Central Nervous System/embryology*
  • Zebrafish/embryology
  • Zebrafish/genetics*
PubMed
10767318 Full text @ Hum. Mol. Genet.
Abstract
The central nervous system (CNS) is the most complex tissue of vertebrates. Recently, the zebrafish has emerged as a powerful genetic system for studying early development, and large-scale mutagenic screens for embryonic patterning defects have been accomplished. Mutants isolated in these screens are proving helpful in unravelling the mole-cular hierarchies involved in the development of the CNS. We review here recent studies in zebrafish which shed light on the genetic pathways involved in induction and regionalization of the CNS.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes