ZFIN ID: ZDB-PERS-960805-581
Vihtelic, Thomas
Email: thomas.vihtelic@mpiresearch.com
Affiliation: University of Notre Dame Center for Zebrafish Research
Address: Department of Biological Sciences University of Notre Dame 107 Galvin Life Science Center Notre Dame, IN 46556 USA
Country: United States
Phone: (574) 631-2895
Fax: (574) 631-7413

Molecular genetics of retina and lens development and function.

Murphy, T.R., Vihtelic, T.S., Ile, K.E., Watson, C.T., Willer, G.B., Gregg, R.G., Bankaitis, V.A., and Hyde, D.R. (2011) Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye. Experimental Eye Research. 93(4):460-74
Thomas, J.L., Vihtelic, T.S., Dendekker, A.D., Willer, G., Luo, X., Murphy, T.R., Gregg, R.G., Hyde, D.R., and Thummel, R. (2011) The loss of vacuolar protein sorting 11 (vps11) causes retinal pathogenesis in a vertebrate model of syndromic albinism. Investigative ophthalmology & visual science. 52(6):3119-28
Calinescu, A.A., Vihtelic, T.S., Hyde, D.R., and Hitchcock, P.F. (2009) Cellular expression of Midkine-a and Midkine-b during retinal development and photoreceptor regeneration in zebrafish. The Journal of comparative neurology. 514(1):1-10
Stenkamp, D.L., Satterfield, R., Muhunthan, K., Sherpa, T., Vihtelic, T.S., and Cameron, D. (2008) Age-Related Cone Abnormalities in Zebrafish with Genetic Lesions in Sonic Hedgehog. Investigative ophthalmology & visual science. 49(10):4631-4640
Harding, R.L., Howley, S., Baker, L.J., Murphy, T.R., Archer, W.E., Wistow, G., Hyde, D.R., and Vihtelic, T.S. (2008) Lengsin expression and function during zebrafish lens formation. Experimental Eye Research. 86(5):807-818
Vihtelic, T.S. (2008) Chapter 6 teleost lens development and degeneration. International review of cell and molecular biology. 269:341-373
Alvarez, Y., Cederlund, M.L., Cottell, D.C., Bill, B.R., Ekker, S.C., Torres-Vazquez, J., Weinstein, B.M., Hyde, D.R., Vihtelic, T.S., and Kennedy, B.N. (2007) Genetic determinants of hyaloid and retinal vasculature in zebrafish. BMC Developmental Biology. 7(1):114
Kassen, S.C., Ramanan, V., Montgomery, J.E., Burket, C.T., Liu, C.G., Vihtelic, T.S., and Hyde, D.R. (2007) Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish. Developmental Neurobiology. 67(8):1009-1031
Semina, E.V., Bosenko, D.V., Zinkevich, N.C., Soules, K.A., Hyde, D.R., Vihtelic, T.S., Willer, G.B., Gregg, R.G., and Link, B.A. (2006) Mutations in laminin alpha 1 result in complex, lens-independent ocular phenotypes in zebrafish. Developmental Biology. 299(1):63-77
Shi, X., Luo, Y., Howley, S., Dzialo, A., Foley, S., Hyde, D.R., and Vihtelic, T.S. (2006) Zebrafish foxe3: Roles in ocular lens morphogenesis through interaction with pitx3. Mechanisms of Development. 123(10):761-782
Vihtelic, T.S., Soverly, J.E., Kassen, S.C., and Hyde, D.R. (2006) Retinal regional differences in photoreceptor cell death and regeneration in light-lesioned albino zebrafish. Experimental Eye Research. 82(4):558-575
Smith, A.A., Wyatt, K., Vacha, J., Vihtelic, T.S., Samuel Zigler, J. Jr, Wistow, G.J., and Posner, M. (2006) Gene duplication and separation of functions in alphaB-crystallin from zebrafish (Danio rerio). The FEBS journal. 273(3):481-490
Vihtelic, T.S., Fadool, J.M., Gao, J., Thornton, K.A., Hyde, D.R., and Wistow, G. (2005) Expressed sequence tag analysis of zebrafish eye tissues for NEIBank. Molecular Vision. 11:1083-1100
Vihtelic, T.S., Yamamoto, Y., Springer, S.S., Jeffery, W.R., and Hyde, D.R. (2005) Lens opacity and photoreceptor degeneration in the zebrafish lens opaque mutant. Developmental Dynamics : an official publication of the American Association of Anatomists. 233(1):52-65
Wistow, G., Wyatt, K., David, L., Gao, C., Bateman, O., Bernstein, S., Tomarev, S., Segovia, L., Slingsby, C., and Vihtelic, T. (2005) gammaN-crystallin and the evolution of the betagamma-crystallin superfamily in vertebrates. The FEBS journal. 272(9):2276-2291
Shi, X., Bosenko, D.V., Zinkevich, N.S., Foley, S., Hyde, D.R., Semina, E.V., and Vihtelic, T.S. (2005) Zebrafish pitx3 is necessary for normal lens and retinal development. Mechanisms of Development. 122(4):513-527
Vihtelic, T.S. and Hyde, D.R. (2002) Zebrafish mutagenesis yields eye morphological mutants with retinal and lens defects. Vision Research. 42(4):535-540
Vihtelic, T.S., Yamamoto, Y., Sweeney, M.T., Jeffery, W.R., and Hyde, D.R. (2001) Arrested differentiation and epithelial cell degeneration in zebrafish lens mutants. Developmental Dynamics : an official publication of the American Association of Anatomists. 222(4):625-636
Kennedy, B.N., Vihtelic, T.S., Checkley, L., Vaughan, K.T., and Hyde, D.R. (2001) Isolation of a zebrafish rod opsin promoter to generate a transgenic zebrafish line expressing EGFP in rod photoreceptors. The Journal of biological chemistry. 276(17):14037-14043
Vihtelic, T.S., Huijbregts, R.P., Watkins, W.A., Bankaitis, V.A., and Hyde, D.R. (2001) Identification and characterization of the zebrafish PITP beta: a protein expressed at high levels in the double cone cell synapse. Investigative ophthalmology & visual science. 42(4):1036
Vihtelic, T.S. and Hyde, D.R. (2000) Light-induced rod and cone cell death and regeneration in the adult albino zebrafish (Danio rerio) retina. Journal of neurobiology. 44(3):289-307
Elagin, V.A., Elagina, R.B., Doro, C.J., Vihtelic, T.S., and Hyde, D.R. (2000) Cloning and tissue localization of a novel zebrafish RdgB homolog that lacks a phospholipid transfer domain. Visual neuroscience. 17(2):303-311
Vihtelic, T.S., Doro, C.J., and Hyde, D.R. (1999) Cloning and characterization of six zebrafish photoreceptor opsin cDNAs and immunolocalization of their corresponding proteins. Visual neuroscience. 16:571-585