ZFIN ID: ZDB-LAB-991007-10
Pelegri Lab
PI/Director: Pelegri, Francisco
Contact Person: Voss, Nik
Email: ngvoss@wisc.edu
URL:
Address: Department of Genetics University of Wisconsin-Madison 410 Genetics Building 445 Henry Mall Madison, WI 53706-1574 USA
Country: United States
Phone: (608) 262-2920
Fax: (608) 262-2976
Line Designation: uw


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 13 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Yabe, Taijirou Post-Doc Brown, Kimberly Graduate Student Ge, Xiaoyan Graduate Student
Putiri, Emily Graduate Student Voss, Nik


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Eno, C., Hansen, C.L., Pelegri, F. (2019) Aggregation, segregation and dispersal of homotypic germ plasm RNPs in the early zebrafish embryo. Developmental dynamics : an official publication of the American Association of Anatomists. 248(4):306-318
Moravec, C.E., Pelegri, F.J. (2019) An Accessible Protocol for the Generation of CRISPR-Cas9 Knockouts Using INDELs in Zebrafish. Methods in molecular biology (Clifton, N.J.). 1920:377-392
Eno, C., Pelegri, F. (2018) Modulation of F-actin dynamics by maternal mid1ip1L controls germ plasm aggregation and furrow recruitment in the zebrafish embryo. Development (Cambridge, England). 145(10)
Eno, C., Gomez, T., Slusarski, D.C., Pelegri, F. (2018) Slow calcium waves mediate furrow microtubule reorganization and germ plasm compaction in the early zebrafish embryo. Development (Cambridge, England). 145(10)
Welch, E.L., Eno, C.C., Nair, S., Lindeman, R.E., Pelegri, F. (2017) Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish. Journal of visualized experiments : JoVE. (122)
Baars, D.L., Takle, K.A., Heier, J., Pelegri, F. (2016) Ploidy Manipulation of Zebrafish Embryos with Heat Shock 2 Treatment. Journal of visualized experiments : JoVE. (118)
Zampedri, C., Tinoco-Cuellar, M., Carrillo-Rosas, S., Diaz-Tellez, A., Ramos-Balderas, J.L., Pelegri, F., Maldonado, E. (2016) Zebrafish P54 RNA helicases are cytoplasmic granule residents that are required for development and stress resilience. Biology Open. 5(10):1473-1484
Yabe, T., Hoshijima, K., Yamamoto, T., Takada, S. (2016) Mesp quadruple zebrafish mutant reveals different roles of mesp genes in somite segmentation between mouse and zebrafish. Development (Cambridge, England). 143(15):2842-52
Eno, C., Solanki, B., Pelegri, F. (2016) aura/mid1ip1L regulates the cytoskeleton at the zebrafish egg-to-embryo transition. Development (Cambridge, England). 143(9):1585-99
Pelegri, F., Mullins, M.C. (2016) Genetic screens for mutations affecting adult traits and parental-effect genes. Methods in cell biology. 135:39-87
Heier, J., Takle, K.A., Hasley, A.O., Pelegri, F. (2015) Ploidy manipulation and induction of alternate cleavage patterns through inhibition of centrosome duplication in the early zebrafish embryo. Developmental dynamics : an official publication of the American Association of Anatomists. 244(10):1300-12
Wanglar, C., Takahashi, J., Yabe, T., Takada, S. (2014) Tbx Protein Level Critical for Clock-Mediated Somite Positioning Is Regulated through Interaction between Tbx and Ripply. PLoS One. 9:e107928
Ge, X., Grotjahn, D., Welch, E., Lyman-Gingerich, J., Holguin, C., Dimitrova, E., Abrams, E.W., Gupta, T., Marlow, F.L., Yabe, T., Adler, A., Mullins, M.C., Pelegri, F. (2014) Hecate/Grip2a acts to reorganize the cytoskeleton in the symmetry-breaking event of embryonic axis induction. PLoS Genetics. 10(6):e1004422
Kimura, T., Nagao, Y., Hashimoto, H., Yamamoto-Shiraishi, Y., Yamamoto, S., Yabe, T., Takada, S., Kinoshita, M., Kuroiwa, A., and Naruse, K. (2014) Leucophores are similar to xanthophores in their specification and differentiation processes in medaka. Proceedings of the National Academy of Sciences of the United States of America. 111(20):7343-7348
Welch, E., Pelegri, F. (2014) Cortical depth and differential transport of vegetally localized dorsal and germ line determinants in the zebrafish embryo. Bioarchitecture. 5(1-2):13-26
Eno, C., Pelegri, F. (2013) Gradual recruitment and selective clearing generate germ plasm aggregates in the zebrafish embryo. Bioarchitecture. 3:125-32
Nair, S., Marlow, F., Abrams, E., Kapp, L., Mullins, M.C., and Pelegri, F. (2013) The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo. PLoS Genetics. 9(4):e1003448
Nair, S., Lindeman, R.E., and Pelegri, F. (2013) In vitro oocyte culture-based manipulation of zebrafish maternal genes. Developmental dynamics : an official publication of the American Association of Anatomists. 242(1):44-52
Yabe, T., and Takada, S. (2012) Mesogenin causes embryonic mesoderm progenitors to differentiate during development of zebrafish tail somites. Developmental Biology. 370(2):213-222
Lindeman, R.E., and Pelegri, F. (2012) Localized Products of futile cycle/ lrmp Promote Centrosome-Nucleus Attachment in the Zebrafish Zygote. Current biology : CB. 22(10):843-851
Frazer, J.K., Batchelor, L.A., Bradley, D.F., Brown, K.H., Dobrinski, K.P., Lee, C., and Trede, N.S. (2012) Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies. Advances in hematology. 2012:627920
Rudner, L.A., Brown, K.H., Dobrinski, K.P., Bradley, D.F., Garcia, M.I., Smith, A.C., Downie, J.M., Meeker, N.D., Look, A.T., Downing, J.R., Gutierrez, A., Mullighan, C.G., Schiffman, J.D., Lee, C., Trede, N.S., and Frazer, J.K. (2011) Shared acquired genomic changes in zebrafish and human T-ALL. Oncogene. 30(41):4289-96
Putiri, E., and Pelegri, F. (2011) The zebrafish maternal-effect gene mission impossible encodes the DEAH-box helicase Dhx16 and is essential for the expression of downstream endodermal genes. Developmental Biology. 353(2):275-289
Dobrinski, K.P., Brown, K.H., Freeman, J.L., and Lee, C. (2011) Molecular Cytogenetic Methodologies and a BAC Probe Panel Resource for Genomic Analyses in the Zebrafish. Methods in cell biology. 104:237-257
Nair, S., and Pelegri, F.J. (2011) Practical approaches for implementing forward genetic strategies in zebrafish. Methods in molecular biology (Clifton, N.J.). 770:185-209
Pelegri, F., and Mullins, M.C. (2011) Genetic Screens for Mutations Affecting Adult Traits and Parental-effect Genes. Methods in cell biology. 104:83-120
Branam, A.M., Hoffman, G.G., Pelegri, F., and Greenspan, D.S. (2010) Zebrafish Chordin-like and Chordin Are Functionally Redundant in Regulating Patterning of the Dorsoventral Axis. Developmental Biology. 341(2):444-458
Hoffman, G.G., Branam, A.M., Huang, G., Pelegri, F., Cole, W.G., Wenstrup, R.M., and Greenspan, D.S. (2010) Characterization of the Six Zebrafish Clade B Fibrillar Procollagen Genes, with Evidence for Evolutionarily Conserved Alternative Splicing within the pro-alpha1(V) C-propeptide. Matrix biology : journal of the International Society for Matrix Biology. 29(4):261-275
Lindeman, R.E., and Pelegri, F. (2010) Vertebrate maternal-effect genes: Insights into fertilization, early cleavage divisions, and germ cell determinant localization from studies in the zebrafish. Molecular reproduction and development. 77(4):299-313
Kim, Y.C., Clark, R.J., Pelegri, F., and Alexander, C.M. (2009) Wnt4 is not sufficient to induce lobuloalveolar mammary development. BMC Developmental Biology. 9:55
Yabe, T., Ge, X., Lindeman, R., Nair, S., Runke, G., Mullins, M.C., and Pelegri, F. (2009) The maternal-effect gene cellular island encodes aurora B kinase and is essential for furrow formation in the early zebrafish embryo. PLoS Genetics. 5(6):e1000518
Ge, X., Link, B.A., and Pelegri, F. (2009) Cell cycle control in the zebrafish. In Cell cycle control in vertebrates (J. Kubiak, M.A. Ciemerych and L. Richard-Parpaillon, Eds.). :9-54
Yabe, T., Ge, X., and Pelegri, F. (2007) The zebrafish maternal-effect gene cellular atoll encodes the centriolar component sas-6 and defects in its paternal function promote whole genome duplication. Developmental Biology. 312(1):44-60
Lyman-Gingerich, J., and Pelegri, F. (2007) Maternal factors in fish oogenesis and embryonic development. The Fish Oocyte. :141-174
Slusarski, D.C., and Pelegri, F. (2007) Calcium signaling in vertebrate embryonic patterning and morphogenesis. Developmental Biology. 307(1):1-13
Jasuja, R., Ge, G., Voss, N.G., Lyman-Gingerich, J., Branam, A.M., Pelegri, F.J., and Greenspan, D.S. (2007) Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4. The Journal of biological chemistry. 282(12):9053-9062
Urven, L.E., Yabe, T., and Pelegri, F. (2006) A role for non-muscle myosin II function in furrow maturation in the early zebrafish embryo. Journal of Cell Science. 119(20):4342-4352
Lyman Gingerich, J., Lindeman, R., Putiri, E., Stolzmann, K., and Pelegri, F. (2006) Analysis of axis induction mutant embryos reveals morphogenetic events associated with zebrafish yolk extension formation. Developmental dynamics : an official publication of the American Association of Anatomists. 235(10):2749-2760
Jasuja, R., Voss, N., Ge, G., Hoffman, G.G., Lyman-Gingerich, J., Pelegri, F., and Greenspan, D.S. (2006) bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis. Mechanisms of Development. 123(7):548-558
Muraoka, O., Shimizu, T., Yabe, T., Nojima, H., Bae, Y.K., Hashimoto, H., and Hibi, M. (2006) Sizzled controls dorso-ventral polarity by repressing cleavage of the Chordin protein. Nature cell biology. 8(4):329-340
Theusch, E.V., Brown, K.J., and Pelegri, F. (2006) Separate pathways of RNA recruitment lead to the compartmentalization of the zebrafish germ plasm. Developmental Biology. 292(1):129-141
Lyman Gingerich, J., Westfall, T.A., Slusarski, D.C., and Pelegri, F. (2005) hecate, a zebrafish maternal effect gene, affects dorsal organizer induction and intracellular calcium transient frequency. Developmental Biology. 286(2):427-439
Shimizu, T., Yabe, T., Muraoka, O., Yonemura, S., Aramaki, S., Hatta, K., Bae, Y.K., Nojima, H., and Hibi, M. (2005) E-cadherin is required for gastrulation cell movements in zebrafish. Mechanisms of Development. 122(6):747-763
Pelegri, F. (2004) The Role of Maternal Factors in Early Zebrafish Development. In Fish Development and Genetics - the Zebrafish and Medaka Models. Gong, Z. and Korh, V., Eds. Book series of "Molecular Aspects of Fish and Marine Biology". 2:1-38
Pelegri, F., Dekens, M.P., Schulte-Merker, S., Maischein, H.M., Weiler, C., and Nüsslein-Volhard, C. (2004) Identification of recessive maternal-effect mutations in the zebrafish using a gynogenesis-based method. Developmental dynamics : an official publication of the American Association of Anatomists. 231(2):324-335
Bae, Y.K., Shimizu, T., Muraoka, O., Yabe, T., Hirata, T., Nojima, H., Hirano, T., and Hibi, M. (2004) Expression of sax1/nkx1.2 and sax2/nkx1.1 in zebrafish. Gene expression patterns : GEP. 4(4):481-486
Nojima, H., Shimizu, T., Kim, C.H., Yabe, T., Bae, Y.K., Muraoka, O., Hirata, T., Chitnis, A., Hirano, T., and Hibi, M. (2004) Genetic evidence for involvement of maternally derived Wnt canonical signaling in dorsal determination in zebrafish. Mechanisms of Development. 121(4):371-386
Pelegri, F., and Mullins, M.C. (2004) Genetic screens for maternal-effect mutations. The Zebrafish: Genetics, Genomics and Informatics, 2nd ed., Methods Cell Biol.. 77:21-51
Pelegri, F. (2003) Maternal factors in zebrafish development. Developmental dynamics : an official publication of the American Association of Anatomists. 228(3):535-554
Dekens, M.P., Pelegri, F.J., Maischein, H.M., and Nüsslein-Volhard, C. (2003) The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote. Development (Cambridge, England). 130(17):3907-3916
Yabe, T., Shimizu, T., Muraoka, O., Bae, Y.-K., Hirata, T., Nojima, H., Kawakami, A., Hirano, T., and Hibi, M. (2003) Ogon/Secreted Frizzled functions as a negative feedback regulator of Bmp signaling. Development (Cambridge, England). 130(12):2705-2716
Bae, Y.K., Shimizu, T., Yabe, T., Kim, C.H., Hirata, T., Nojima, H., Muraoka, O., Hirano, T., and Hibi, M. (2003) A homeobox gene, pnx, is involved in the formation of posterior neurons in zebrafish. Development (Cambridge, England). 130(9):1853-1865
Pelegri, F. (2002) Mutagenesis. In Zebrafish: A Practical Approach, S. Schulte-Merker and C. Nüsslein-Volhard, eds. IRL Press. 261:145-174
Shimizu, T., Yamanaka, Y., Nojima, H., Yabe, T., Hibi, M., and Hirano, T. (2002) A novel repressor-type homeobox gene, ved, is involved in dharma/bozozok-mediated dorsal organizer formation in zebrafish. Mechanisms of Development. 118(1-2):125-38
Ryu, S.-L., Fujii, R., Yamanaka, Y., Shimizu, T., Yabe, T., Hirata, T., Hibi, M., and Hirano, T. (2001) Regulation of dharma/bozozok by the Wnt Pathway. Developmental Biology. 231(2):397-409
Hashimoto, H., Yabe, T., Hirata, T., Shimizu, T., Bae, Y., Yamanaka, Y., Hirano, T., and Hibi, M. (2000) Expression of the zinc finger gene fez-like in zebrafish forebrain. Mechanisms of Development. 97(1-2):191-195
Hirata, T., Yamanaka, Y., Ryu, S.L., Shimizu, T., Yabe, T., Hibi, M., and Hirano, T. (2000) Novel mix-family homeobox genes in zebrafish and their differential regulation. Biochemical and Biophysical Research Communications. 271(3):603-609
Knaut, H., Pelegri, F., Bohmann, K., Schwarz, H., and Nüsslein-Volhard, C. (2000) Zebrafish vasa RNA but not its protein is a component of the germ plasm and segregates asymmetrically before germline specification. The Journal of cell biology. 149(4):875-888
Shimizu, T., Yamanaka, Y., Ryu, S., Hashimoto, H., Yabe, T., Hirata, T., Bae, Y., Hibi, M., and Hirano, T. (2000) Cooperative roles of Bozozok/Dharma and Nodal-related proteins in the formation of the dorsal organizer in zebrafish. Mechanisms of Development. 91(1-2):293-303
Pelegri, F., Knaut, H., Maischein, H.M., Schulte-Merker, S., and Nüsslein-Volhard, C. (1999) A mutation in the zebrafish maternal-effect gene nebel affects furrow formation and vasa RNA localization. Current biology : CB. 9(24):1431-1440
Geisler, R., Rauch, G.J., Baier, H., van Bebber, F., Brobeta, L., Dekens, M.P., Finger, K., Fricke, C., Gates, M.A., Geiger, H., Geiger-Rudolph, S., Gilmour, D., Glaser, S., Gnugge, L., Habeck, H., Hingst, K., Holley, S., Keenan, J., Kirn, A., Knaut, H., Lashkari, D., Maderspacher, F., Martyn, U., Neuhauss, S., Neumann, C., Nicolson, T., Pelegri, F., Ray, R., Rick, J.M., Roehl, H., Roeser, T., Schauerte, H.E., Schier, A.F., Schönberger, U., Schönthaler, H.-B., Schulte-Merker, S., Seydler, C., Talbot, W.S., Weiler, C., Nüsslein-Volhard, C., and Haffter, P. (1999) A radiation hybrid map of the zebrafish genome. Nature Genetics. 23(1):86-89
Pelegri, F. and Schulte-Merker, S. (1999) A gynogenesis-based screen for maternal-effect genes in the zebrafish, Danio rerio. In The Zebrafish: Genetics and Genomics, H.W. Detrich, III, M. Westerfield, and L.I. Zon, eds., San Diego, CA: Academic Press, Methods Cell Biol.. 60:1-20
Pelegri, F. and Maischein, H.M. (1998) Function of zebrafish ß-catenin and TCF-3 in dorsoventral patterning. Mechanisms of Development. 77:63-74
Brand, M., Heisenberg, C.P., Warga, R.M., Pelegri, F., Karlstrom, R.O., Beuchle, D., Picker, A., Jiang, Y.J., Furutani-Seiki, M., van Eeden, F.J., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D.A., Kelsh, R.N., Mullins, M.C., Odenthal, J., and Nüsslein-Volhard, C. (1996) Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. Development (Cambridge, England). 123:129-142
Hammerschmidt, M., Pelegri, F., Mullins, M.C., Kane, D.A., Brand, M., van Eeden, F.J., Furutani-Seiki, M., Granato, M., Haffter, P., Heisenberg, C.P., Jiang, Y.J., Kelsh, R.N., Odenthal, J., Warga, R.M., and Nüsslein-Volhard, C. (1996) Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. Development (Cambridge, England). 123:143-151
Hammerschmidt, M., Pelegri, F., Mullins, M.C., Kane, D.A., van Eeden, F.J., Granato, M., Brand, M., Furutani-Seiki, M., Haffter, P., Heisenberg, C.P., Jiang, Y.J., Kelsh, R.N., Odenthal, J., Warga, R.M., and Nüsslein-Volhard, C. (1996) dino and mercedes, two genes regulating dorsal development in the zebrafish embryo. Development (Cambridge, England). 123:95-102