ZFIN ID: ZDB-LAB-150617-1
Vermot Lab
PI/Director: Vermot, Julien
Contact Person: Roth, Stéphane
Email: roth@igbmc.fr
URL:
Address:
Country:
Phone: 33388655718/5633
Fax: 33 3 88 65 32 01
Line Designation: ig


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 6 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Boselli, Francesco Post-Doc Campinho, Pedro Post-Doc Peralta López, Marina Post-Doc
Steed, Emily Post-Doc Faggianelli, Nathalie Graduate Student Ferreira, Rita Graduate Student
Roth, Stéphane Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Campinho, P., Lamperti, P., Boselli, F., Vilfan, A., Vermot, J. (2020) Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta. Cell Reports. 31:107505
Duchemin, A.L., Vignes, H., Vermot, J. (2019) Mechanically activated Piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis. eLIFE. 8:
Gálvez-Santisteban, M., Chen, D., Zhang, R., Serrano, R., Nguyen, C., Zhao, L., Nerb, L., Masutani, E.M., Vermot, J., Burns, C.G., Burns, C.E., Del Álamo, J.C., Chi, N.C. (2019) Hemodynamic-mediated endocardial signaling controls in vivo myocardial reprogramming. eLIFE. 8:
Andrés-Delgado, L., Ernst, A., Galardi-Castilla, M., Bazaga, D., Peralta, M., Münch, J., González-Rosa, J.M., Marques, I., Tessadori, F., de la Pompa, J.L., Vermot, J., Mercader, N. (2019) Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells. Development (Cambridge, England). 146(13):
Ferreira, R.R., Pakula, G., Klaeyle, L., Fukui, H., Vilfan, A., Supatto, W., Vermot, J. (2018) Chiral Cilia Orientation in the Left-Right Organizer. Cell Reports. 25:2008-2016.e4
Campinho, P., Lamperti, P., Boselli, F., Vermot, J. (2018) Three-dimensional microscopy and image analysis methodology for mapping and quantification of nuclear positions in tissues with approximate cylindrical geometry. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 373(1759):
Fukui, H., Miyazaki, T., Chow, R.W., Ishikawa, H., Nakajima, H., Vermot, J., Mochizuki, N. (2018) Hippo signaling determines the number of venous pole cells that originate from the anterior lateral plate mesoderm in zebrafish. eLIFE. 7
Chow, R.W., Lamperti, P., Steed, E., Boselli, F., Vermot, J. (2018) Following Endocardial Tissue Movements via Cell Photoconversion in the Zebrafish Embryo. Journal of visualized experiments : JoVE. (132)
Boselli, F., Steed, E., Freund, J.B., Vermot, J. (2017) Anisotropic shear stress patterns predict the orientation of convergent tissue movements in the embryonic heart. Development (Cambridge, England). 144:4322-4327
Goddard, L.M., Duchemin, A.L., Ramalingan, H., Wu, B., Chen, M., Bamezai, S., Yang, J., Li, L., Morley, M.P., Wang, T., Scherrer-Crosbie, M., Frank, D.B., Engleka, K.A., Jameson, S.C., Morrisey, E.E., Carroll, T.J., Zhou, B., Vermot, J., Kahn, M.L. (2017) Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis. Developmental Cell. 43(3):274-289.e5
Bouchaala, R., Anton, N., Anton, H., Vandamme, T., Vermot, J., Smail, D., Mély, Y., Klymchenko, A.S. (2017) Light-triggered release from dye-loaded fluorescent lipid nanocarriers in vitro and in vivo. Colloids and surfaces. B, Biointerfaces. 156:414-421
Ferreira, R.R., Vilfan, A., Jülicher, F., Supatto, W., Vermot, J. (2017) Physical limits of flow sensing in the left-right organizer. eLIFE. 6
Chow, R.W., Vermot, J. (2017) The rise of photoresponsive protein technologies applications in vivo: a spotlight on zebrafish developmental and cell biology.. F1000Research. 6
Ferreira, R.R., Vermot, J. (2017) The balancing roles of mechanical forces during left-right patterning and asymmetric morphogenesis. Mechanisms of Development. 144:71-80
Jacob, L., Sawma, P., Garnier, N., Meyer, L.A., Fritz, J., Hussenet, T., Spenlé, C., Goetz, J., Vermot, J., Fernandez, A., Baumlin, N., Aci-Sèche, S., Orend, G., Roussel, G., Crémel, G., Genest, M., Hubert, P., Bagnard, D. (2016) Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide. Oncotarget. 7:57851-57865
Steed, E., Boselli, F., Vermot, J. (2016) Hemodynamics driven cardiac valve morphogenesis. Biochimica et biophysica acta. Molecular cell research. 1863(7 Pt B):1760-6
Steed, E., Faggianelli, N., Roth, S., Ramspacher, C., Concordet, J.P., Vermot, J. (2016) klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. Nature communications. 7:11646
Boselli, F., Vermot, J. (2016) Live imaging and modeling for shear stress quantification in the embryonic zebrafish heart. Methods (San Diego, Calif.). 94:129-34
Ramspacher, C., Steed, E., Boselli, F., Ferreira, R., Faggianelli, N., Roth, S., Spiegelhalter, C., Messaddeq, N., Trinh, L., Liebling, M., Chacko, N., Tessadori, F., Bakkers, J., Laporte, J., Hnia, K., Vermot, J. (2015) Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies. Cell Reports. 11:1564-76
Heckel, E., Boselli, F., Roth, S., Krudewig, A., Belting, H. G., Charvin, G., Vermot, J. (2015) Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development. Current biology : CB. 25(10):1354-1361
Renz, M., Otten, C., Faurobert, E., Rudolph, F., Zhu, Y., Boulday, G., Duchene, J., Mickoleit, M., Dietrich, A.C., Ramspacher, C., Steed, E., Manet-Dupé, S., Benz, A., Hassel, D., Vermot, J., Huisken, J., Tournier-Lasserve, E., Felbor, U., Sure, U., Albiges-Rizo, C., Abdelilah-Seyfried, S. (2015) Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins. Developmental Cell. 32:181-190
Boselli, F., Goetz, J.G., Charvin, G., Vermot, J. (2015) A quantitative approach to study endothelial cilia bending stiffness during blood flow mechanodetection in vivo. Methods in cell biology. 127:161-73
Goetz, J.G., Monduc, F., Schwab, Y., Vermot, J. (2015) Using correlative light and electron microscopy to study zebrafish vascular morphogenesis. Methods in molecular biology (Clifton, N.J.). 1189:31-46
Smutny, M., Behrndt, M., Campinho, P., Ruprecht, V., Heisenberg, C.P. (2015) UV Laser Ablation to Measure Cell and Tissue-Generated Forces in the Zebrafish Embryo In Vivo and Ex Vivo. Methods in molecular biology (Clifton, N.J.). 1189:219-35
Kilin, V.N., Anton, H., Anton, N., Steed, E., Vermot, J., Vandamme, T.F., Mely, Y., Klymchenko, A.S. (2014) Counterion-enhanced cyanine dye loading into lipid nano-droplets for single-particle tracking in zebrafish. Biomaterials. 35:4950-7
Peralta, M., González-Rosa, J.M., Marques, I.J., Mercader, N. (2014) The Epicardium in the Embryonic and Adult Zebrafish. Journal of developmental biology. 2:101-116
Goetz, J.G., Steed, E., Ferreira, R.R., Roth, S., Ramspacher, C., Boselli, F., Charvin, G., Liebling, M., Wyart, C., Schwab, Y., Vermot, J. (2014) Endothelial cilia mediate low flow sensing during zebrafish vascular development. Cell Reports. 6:799-808
Campinho, P., Behrndt, M., Ranft, J., Risler, T., Minc, N., and Heisenberg, C.P. (2013) Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading during zebrafish epiboly. Nature cell biology. 15(12):1405-1414
Anton, H., Harlepp, S., Ramspacher, C., Wu, D., Monduc, F., Bhat, S., Liebling, M., Paoletti, C., Charvin, G., Freund, J.B., and Vermot, J. (2013) Pulse propagation by a capacitive mechanism drives embryonic blood flow. Development (Cambridge, England). 140(21):4426-34
Peralta, M., Steed, E., Harlepp, S., González-Rosa, J.M., Monduc, F., Ariza-Cosano, A., Cortés, A., Rayón, T., Gómez-Skarmeta, J.L., Zapata, A., Vermot, J., and Mercader, N. (2013) Heartbeat-Driven Pericardiac Fluid Forces Contribute to Epicardium Morphogenesis. Current biology : CB. 23(18):1726-35
Koutsopoulos, O.S., Kretz, C., Weller, C.M., Roux, A., Mojzisova, H., Böhm, J., Koch, C., Toussaint, A., Heckel, E., Stemkens, D., Ter Horst, S.A., Thibault, C., Koch, M., Mehdi, S.Q., Bijlsma, E.K., Mandel, J.L., Vermot, J., and Laporte, J. (2013) Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome. European journal of human genetics : EJHG. 21(6):637-42
Behrndt, M., Salbreux, G., Campinho, P., Hauschild, R., Oswald, F., Roensch, J., Grill, S.W., and Heisenberg, C.P. (2012) Forces driving epithelial spreading in zebrafish gastrulation. Science (New York, N.Y.). 338(6104):257-260
Freund, J.B., Goetz, J.G., Hill, K.L., and Vermot, J. (2012) Fluid flows and forces in development: functions, features and biophysical principles. Development (Cambridge, England). 139(7):1229-1245
Supatto, W., and Vermot, J. (2011) From cilia hydrodynamics to zebrafish embryonic development. Current topics in developmental biology. 95:33-66
Soyer, J., Flasse, L., Raffelsberger, W., Beucher, A., Orvain, C., Peers, B., Ravassard, P., Vermot, J., Voz, M.L., Mellitzer, G., and Gradwohl, G. (2010) Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development (Cambridge, England). 137(2):203-212
Vermot, J., Forouhar, A.S., Liebling, M., Wu, D., Plummer, D., Gharib, M., and Fraser, S.E. (2009) Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart. PLoS Biology. 7(11):e1000246
Colantonio, J.R., Vermot, J., Wu, D., Langenbacher, A.D., Fraser, S., Chen, J.N., and Hill, K.L. (2009) The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear. Nature. 457(7226):205-209
Supatto, W., Fraser, S.E., and Vermot, J. (2008) An All-Optical Approach for Probing Microscopic Flows in Living Embryos. Biophysical journal. 95(4):L29-L31