ZFIN Person: Vermot, Julien

ZFIN ID: ZDB-PERS-101028-1

ZFIN ID: ZDB-PERS-101028-1

Vermot, Julien

Email:	julien@igbmc.fr
URL:
Affiliation:	Vermot Lab
Address:	IGBMC 1 rue Laurent Fries Illkirch, 67 404 France
Country:	France
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Cairelli, A.G., Chow, R.W., Vermot, J., Yap, C.H. (2022) Fluid mechanics of the zebrafish embryonic heart trabeculation. PLoS Computational Biology. 18:e1010142

Vignes, H., Vagena-Pantoula, C., Prakash, M., Fukui, H., Norden, C., Mochizuki, N., Jug, F., Vermot, J. (2022) Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis. Developmental Cell. 57(5):598-609.e5

Chow, R.W., Fukui, H., Chan, W.X., Tan, K.S.J., Roth, S., Duchemin, A.L., Messaddeq, N., Nakajima, H., Liu, F., Faggianelli-Conrozier, N., Klymchenko, A.S., Choon Hwai, Y., Mochizuki, N., Vermot, J. (2022) Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling. PLoS Biology. 20:e3001505

Fukui, H., Chow, R.W., Xie, J., Foo, Y.Y., Yap, C.H., Minc, N., Mochizuki, N., Vermot, J. (2021) Bioelectric signaling and the control of cardiac cell identity in response to mechanical forces. Science (New York, N.Y.). 374:351-354

Peralta, M., Ortiz Lopez, L., Jerabkova, K., Lucchesi, T., Vitre, B., Han, D., Guillemot, L., Dingare, C., Sumara, I., Mercader, N., Lecaudey, V., Delaval, B., Meilhac, S.M., Vermot, J. (2020) Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis. Cell Reports. 32:107932

Campinho, P., Vilfan, A., Vermot, J. (2020) Blood Flow Forces in Shaping the Vascular System: A Focus on Endothelial Cell Behavior. Frontiers in Physiology. 11:552

Campinho, P., Lamperti, P., Boselli, F., Vilfan, A., Vermot, J. (2020) Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta. Cell Reports. 31:107505

Duchemin, A.L., Vignes, H., Vermot, J. (2019) Mechanically activated Piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis. eLIFE. 8:

Gálvez-Santisteban, M., Chen, D., Zhang, R., Serrano, R., Nguyen, C., Zhao, L., Nerb, L., Masutani, E.M., Vermot, J., Burns, C.G., Burns, C.E., Del Álamo, J.C., Chi, N.C. (2019) Hemodynamic-mediated endocardial signaling controls in vivo myocardial reprogramming. eLIFE. 8:

Andrés-Delgado, L., Ernst, A., Galardi-Castilla, M., Bazaga, D., Peralta, M., Münch, J., González-Rosa, J.M., Marques, I., Tessadori, F., de la Pompa, J.L., Vermot, J., Mercader, N. (2019) Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells. Development (Cambridge, England). 146(13):

Ferreira, R.R., Pakula, G., Klaeyle, L., Fukui, H., Vilfan, A., Supatto, W., Vermot, J. (2018) Chiral Cilia Orientation in the Left-Right Organizer. Cell Reports. 25:2008-2016.e4

Campinho, P., Lamperti, P., Boselli, F., Vermot, J. (2018) Three-dimensional microscopy and image analysis methodology for mapping and quantification of nuclear positions in tissues with approximate cylindrical geometry. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 373(1759):

Fukui, H., Miyazaki, T., Chow, R.W., Ishikawa, H., Nakajima, H., Vermot, J., Mochizuki, N. (2018) Hippo signaling determines the number of venous pole cells that originate from the anterior lateral plate mesoderm in zebrafish. eLIFE. 7

Chow, R.W., Lamperti, P., Steed, E., Boselli, F., Vermot, J. (2018) Following Endocardial Tissue Movements via Cell Photoconversion in the Zebrafish Embryo. Journal of visualized experiments : JoVE. (132)

Boselli, F., Steed, E., Freund, J.B., Vermot, J. (2017) Anisotropic shear stress patterns predict the orientation of convergent tissue movements in the embryonic heart. Development (Cambridge, England). 144:4322-4327

Goddard, L.M., Duchemin, A.L., Ramalingan, H., Wu, B., Chen, M., Bamezai, S., Yang, J., Li, L., Morley, M.P., Wang, T., Scherrer-Crosbie, M., Frank, D.B., Engleka, K.A., Jameson, S.C., Morrisey, E.E., Carroll, T.J., Zhou, B., Vermot, J., Kahn, M.L. (2017) Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis. Developmental Cell. 43(3):274-289.e5

Bouchaala, R., Anton, N., Anton, H., Vandamme, T., Vermot, J., Smail, D., Mély, Y., Klymchenko, A.S. (2017) Light-triggered release from dye-loaded fluorescent lipid nanocarriers in vitro and in vivo. Colloids and surfaces. B, Biointerfaces. 156:414-421

Ferreira, R.R., Vilfan, A., Jülicher, F., Supatto, W., Vermot, J. (2017) Physical limits of flow sensing in the left-right organizer. eLIFE. 6

Chow, R.W., Vermot, J. (2017) The rise of photoresponsive protein technologies applications in vivo: a spotlight on zebrafish developmental and cell biology.. F1000Research. 6

Ferreira, R.R., Vermot, J. (2017) The balancing roles of mechanical forces during left-right patterning and asymmetric morphogenesis. Mechanisms of Development. 144:71-80

Jacob, L., Sawma, P., Garnier, N., Meyer, L.A., Fritz, J., Hussenet, T., Spenlé, C., Goetz, J., Vermot, J., Fernandez, A., Baumlin, N., Aci-Sèche, S., Orend, G., Roussel, G., Crémel, G., Genest, M., Hubert, P., Bagnard, D. (2016) Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide. Oncotarget. 7:57851-57865

Steed, E., Boselli, F., Vermot, J. (2016) Hemodynamics driven cardiac valve morphogenesis. Biochimica et biophysica acta. Molecular cell research. 1863(7 Pt B):1760-6

Steed, E., Faggianelli, N., Roth, S., Ramspacher, C., Concordet, J.P., Vermot, J. (2016) klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. Nature communications. 7:11646

Boselli, F., Vermot, J. (2016) Live imaging and modeling for shear stress quantification in the embryonic zebrafish heart. Methods (San Diego, Calif.). 94:129-34

Ramspacher, C., Steed, E., Boselli, F., Ferreira, R., Faggianelli, N., Roth, S., Spiegelhalter, C., Messaddeq, N., Trinh, L., Liebling, M., Chacko, N., Tessadori, F., Bakkers, J., Laporte, J., Hnia, K., Vermot, J. (2015) Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies. Cell Reports. 11:1564-76

Heckel, E., Boselli, F., Roth, S., Krudewig, A., Belting, H. G., Charvin, G., Vermot, J. (2015) Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development. Current biology : CB. 25(10):1354-1361

Renz, M., Otten, C., Faurobert, E., Rudolph, F., Zhu, Y., Boulday, G., Duchene, J., Mickoleit, M., Dietrich, A.C., Ramspacher, C., Steed, E., Manet-Dupé, S., Benz, A., Hassel, D., Vermot, J., Huisken, J., Tournier-Lasserve, E., Felbor, U., Sure, U., Albiges-Rizo, C., Abdelilah-Seyfried, S. (2015) Regulation of β1 Integrin-Klf2-Mediated Angiogenesis by CCM Proteins. Developmental Cell. 32:181-190

Boselli, F., Goetz, J.G., Charvin, G., Vermot, J. (2015) A quantitative approach to study endothelial cilia bending stiffness during blood flow mechanodetection in vivo. Methods in cell biology. 127:161-73

Goetz, J.G., Monduc, F., Schwab, Y., Vermot, J. (2015) Using correlative light and electron microscopy to study zebrafish vascular morphogenesis. Methods in molecular biology (Clifton, N.J.). 1189:31-46

Kilin, V.N., Anton, H., Anton, N., Steed, E., Vermot, J., Vandamme, T.F., Mely, Y., Klymchenko, A.S. (2014) Counterion-enhanced cyanine dye loading into lipid nano-droplets for single-particle tracking in zebrafish. Biomaterials. 35:4950-7

Goetz, J.G., Steed, E., Ferreira, R.R., Roth, S., Ramspacher, C., Boselli, F., Charvin, G., Liebling, M., Wyart, C., Schwab, Y., Vermot, J. (2014) Endothelial cilia mediate low flow sensing during zebrafish vascular development. Cell Reports. 6:799-808

Anton, H., Harlepp, S., Ramspacher, C., Wu, D., Monduc, F., Bhat, S., Liebling, M., Paoletti, C., Charvin, G., Freund, J.B., and Vermot, J. (2013) Pulse propagation by a capacitive mechanism drives embryonic blood flow. Development (Cambridge, England). 140(21):4426-34

Peralta, M., Steed, E., Harlepp, S., González-Rosa, J.M., Monduc, F., Ariza-Cosano, A., Cortés, A., Rayón, T., Gómez-Skarmeta, J.L., Zapata, A., Vermot, J., and Mercader, N. (2013) Heartbeat-Driven Pericardiac Fluid Forces Contribute to Epicardium Morphogenesis. Current biology : CB. 23(18):1726-35

Koutsopoulos, O.S., Kretz, C., Weller, C.M., Roux, A., Mojzisova, H., Böhm, J., Koch, C., Toussaint, A., Heckel, E., Stemkens, D., Ter Horst, S.A., Thibault, C., Koch, M., Mehdi, S.Q., Bijlsma, E.K., Mandel, J.L., Vermot, J., and Laporte, J. (2013) Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome. European journal of human genetics : EJHG. 21(6):637-42

Freund, J.B., Goetz, J.G., Hill, K.L., and Vermot, J. (2012) Fluid flows and forces in development: functions, features and biophysical principles. Development (Cambridge, England). 139(7):1229-1245

Supatto, W., and Vermot, J. (2011) From cilia hydrodynamics to zebrafish embryonic development. Current topics in developmental biology. 95:33-66

Soyer, J., Flasse, L., Raffelsberger, W., Beucher, A., Orvain, C., Peers, B., Ravassard, P., Vermot, J., Voz, M.L., Mellitzer, G., and Gradwohl, G. (2010) Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development (Cambridge, England). 137(2):203-212

Vermot, J., Forouhar, A.S., Liebling, M., Wu, D., Plummer, D., Gharib, M., and Fraser, S.E. (2009) Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart. PLoS Biology. 7(11):e1000246

Colantonio, J.R., Vermot, J., Wu, D., Langenbacher, A.D., Fraser, S., Chen, J.N., and Hill, K.L. (2009) The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear. Nature. 457(7226):205-209

Supatto, W., Fraser, S.E., and Vermot, J. (2008) An All-Optical Approach for Probing Microscopic Flows in Living Embryos. Biophysical journal. 95(4):L29-L31

NON-ZEBRAFISH PUBLICATIONS