ZFIN ID: ZDB-LAB-131203-3
Yuh Lab
PI/Director: Yuh, Chiou-Hwa (Cathy)
Contact Person: Yang, Wan-Yu
Email: cs081011@nhri.org.tw
URL: http://www.nhri.org.tw/NHRI_WEB/nhriw1001Action.do?emp_cd=931215
Address: #35 Keyan Road, Zhunan Town, Miaoli County, Taiwan, R.O.C. R2-3033, Institute of Molecular and Genomic Medicine, National Health
Country: Taiwan
Phone: 011-886-37-246166 extension 35337
Fax: 011-886-37-586459
Line Designation: nn


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 13 genomic features


STATEMENT OF RESEARCH INTERESTS


LAB MEMBERS
Huang, I-Ping Post-Doc Tsai, Su-Mei Post-Doc Lin, Han-Syuan Graduate Student
Tseng, Bo-Han Graduate Student Tu, Hsiao-Chen Graduate Student Yeh, Lien-Chin Graduate Student
Chang, Kai-Jui Technical Staff Huang, Yi-Luen Technical Staff Yang, Wan-Yu Technical Staff


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Sie, Z.L., Li, R.Y., Sampurna, B.P., Hsu, P.J., Liu, S.C., Wang, H.D., Huang, C.L., Yuh, C.H. (2020) WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis. Cancers. 12(3):
Su, Z.L., Su, C.W., Huang, Y.L., Yang, W.Y., Sampurna, B.P., Ouchi, T., Lee, K.L., Wu, C.S., Wang, H.D., Yuh, C.H. (2019) A Novel AURKA Mutant-Induced Early-Onset Severe Hepatocarcinogenesis Greater than Wild-Type via Activating Different Pathways in Zebrafish. Cancers. 11(7)
Lin, H.S., Huang, Y.L., Wang, Y.S., Hsiao, E., Hsu, T.A., Shiao, H.Y., Jiaang, W.T., Sampurna, B.P., Lin, K.H., Wu, M.S., Lai, G.M., Yuh, C.H. (2019) Identification of Novel Anti-Liver Cancer Small Molecules with Better Therapeutic Index than Sorafenib via Zebrafish Drug Screening Platform. Cancers. 11(6)
Chou, Y.T., Chen, L.Y., Tsai, S.L., Tu, H.C., Lu, J.W., Ciou, S.C., Wang, H.D., Yuh, C.H. (2018) Ribose-5-Phosphate Isomerase A Overexpression Promotes Liver Cancer Development in Transgenic Zebrafish via Activation of ERK and β-catenin Pathways. Carcinogenesis. 40(3):461-473
Chou, Y.T., Jiang, J.K., Yang, M.H., Lu, J.W., Lin, H.K., Wang, H.D., Yuh, C.H. (2018) Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating β-catenin via a novel C-terminal domain. PLoS Biology. 16:e2003714
Wu, S.Y., Chou, H.Y., Yuh, C.H., Mekuria, S.L., Kao, Y.C., Tsai, H.C. (2017) Radiation-Sensitive Dendrimer-Based Drug Delivery System. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 5:1700339
Hsu, D.S., Hwang, W.L., Yuh, C.H., Chu, C.H., Ho, Y.H., Chen, P.B., Lin, H.S., Lin, H.K., Wu, S.P., Lin, C.Y., Hsu, W.H., Lan, H.Y., Wang, H.J., Tai, S.K., Hung, M.C., Yang, M.H. (2017) Lymphotoxin-beta interacts with methylated EGFR to mediate acquired resistance to cetuximab in head and neck cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 23(15):4388-4401
Yang, C.H., Yeh, Y.J., Wang, J.Y., Liu, Y.W., Chen, Y.L., Cheng, H.W., Cheng, C.M., Chuang, Y.J., Yuh, C.H., Chen, Y.R. (2017) NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish. Scientific Reports. 7:5241
Huang, Y.C., Lin, S.J., Shih, H.Y., Chou, C.H., Chu, H.H., Chiu, C.C., Yuh, C.H., Yeh, T.H., Cheng, Y.C. (2017) Epigenetic regulation of NOTCH1 and NOTCH3 by KMT2A inhibits glioma proliferation. Oncotarget. 8:63110-63120
Tu, H.C., Hsiao, Y.C., Yang, W.Y., Tsai, S.L., Lin, H.K., Liao, C.Y., Lu, J.W., Chou, Y.T., Wang, H.D., Yuh, C.H. (2017) Up-regulation of golgi α-mannosidase IA and down-regulation of golgi α-mannosidase IC activates unfolded protein response during hepatocarcinogenesis. Hepatology communications. 1:230-247
You, M.S., Jiang, Y.J., Yuh, C.H., Wang, C.M., Tang, C.H., Chuang, Y.J., Lin, B.H., Wu, J.L., Hwang, S.L. (2016) A Sketch of the Taiwan Zebrafish Core Facility. Zebrafish. 13 Suppl 1:S24-9
Lai, J.G., Tsai, S.M., Tu, H.C., Chen, W.C., Kou, F.J., Lu, J.W., Wang, H.D., Huang, C.L., Yuh, C.H. (2014) Zebrafish WNK Lysine Deficient Protein Kinase 1 (wnk1) Affects Angiogenesis Associated with VEGF Signaling. PLoS One. 9:e106129
Lu, J.W., Liao, C.Y., Yang, W.Y., Lin, Y.M., Jin, S.L., Wang, H.D., and Yuh, C.H. (2014) Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway. PLoS One. 9(1):e85318
Yeh, D.W., Liu, Y.L., Lo, Y.C., Yuh, C.H., Yu, G.Y., Lo, J.F., Luo, Y., Xiang, R., and Chuang, T.H. (2013) Toll-like receptor 9 and 21 have different ligand recognition profiles and cooperatively mediate activity of CpG-oligodeoxynucleotides in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 110(51):20711-20716
Lu, J.W., Yang, W.Y., Tsai, S.M., Lin, Y.M., Chang, P.H., Chen, J.R., Wang, H.D., Wu, J.L., Jin, S.L., and Yuh, C.H. (2013) Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish. PLoS One. 8(10):e76951
Chen, W., Tseng, X., Lin, G., Schreiner, A., Chen, H., Voigt, M.M., Yuh, C., Wu, J., Huang, S.S., and Huang, J. (2013) The Ortholog of LYVE-1 Is Required for Thoracic Duct Formation in Zebrafish. CellBio. 2(4):228-247
Lu, J.W., Yang, W.Y., Lin, Y.M., Jin, S.L., and Yuh, C.H. (2013) Hepatitis B virus X antigen and aflatoxin B1 synergistically cause hepatitis, steatosis and liver hyperplasia in transgenic zebrafish. Acta histochemica. 115(7):728-39
Tsai, S.M., Liu, D.W., and Wang, W.P. (2013) Fibroblast growth factor (Fgf) signaling pathway regulates liver homeostasis in zebrafish. Transgenic Research. 22(2):301-314
Tseng, W.F., Jang, T.H., Huang, C.B., and Yuh, C.H. (2011) An evolutionarily conserved kernel of gata5, gata6, otx2 and prdm1a operates in the formation of endoderm in zebrafish. Developmental Biology. 357(2):541-57
Lu, J.W., Hsia, Y., Tu, H.C., Hsiao, Y.C., Yang, W.Y., Wang, H.D., and Yuh, C.H.. (2011) Liver development and cancer formation in zebrafish. Birth defects research. Part C, Embryo today : reviews. 93(2):157-172
Chao, C.H., Wang, H.D., and Yuh, C.H. (2010) Complexity of cis-regulatory organization of six3a during forebrain and eye development in zebrafish. BMC Developmental Biology. 10:35
Chen, H.L., Yuh, C.H., and Wu, K.K. (2010) Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Apoptosis. PLoS One. 5(2):e9318
Chan, T.M., Longabaugh, W., Bolouri, H., Chen, H.L., Tseng, W.F., Chao, C.H., Jang, T.H., Lin, Y.I., Hung, S.C., Wang, H.D., and Yuh, C.H. (2009) Developmental gene regulatory networks in the zebrafish embryo. Biochimica et biophysica acta. Gene regulatory mechanisms. 1789(4):279-298
Chan, T.M., Chao, C.H., Wang, H.D., Yu, Y.J., and Yuh, C.H. (2009) Functional analysis of the evolutionarily conserved Cis-regulatory elements on the Sox17 gene in zebrafish. Developmental Biology. 326(2):456-470